Found 196 results
N. Gural, Mancio-Silva, L., He, J., and Bhatia, S. N., Engineered Livers for Infectious Diseases, Cellular and Molecular Gastroenterology and Hepatology, vol. 5, no. 2, pp. 131 - 144, 2018.
J. S. Dudani, Warren, A. D., and Bhatia, S. N., Harnessing Protease Activity to Improve Cancer Care, Annual Review of Cancer Biology, vol. 2, no. 1, 2018.
N. K. Kisalu, Idris, A. H., Weidle, C., Flores-Garcia, Y., Flynn, B. J., Sack, B. K., Murphy, S., n, A. ¨, Freire, E., Francica, J. R., Miller, A. B., Gregory, J., March, S., Liao, H. - X., Haynes, B. F., Wiehe, K., Trama, A. M., Saunders, K. O., Gladden, M. A., Monroe, A., Bonsignori, M., Kanekiyo, M., Wheatley, A. K., McDermott, A. B., S Farney, K., Chuang, G. - Y., Zhang, B., Kc, N., Chakravarty, S., Kwong, P. D., Sinnis, P., Bhatia, S. N., Kappe, S. H. I., B Sim, K. Lee, Hoffman, S. L., Zavala, F., Pancera, M., and Seder, R. A., A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite, Nature Medicine, vol. 24, no. 4, pp. 408-416, 2018.
N. Gural, Mancio-Silva, L., Miller, A. B., Galstian, A., Butty, V. L., Levine, S. S., Patrapuvich, R., Desai, S. P., Mikolajczak, S. A., Kappe, S. H. I., Fleming, H. E., March, S., Sattabongkot, J., and Bhatia, S. N., In Vitro Culture, Drug Sensitivity, and Transcriptome of Plasmodium Vivax Hypnozoites, Cell Host & Microbe, vol. 23, no. 3, pp. 395-406, 2018.
M. - E. Gilles, Hao, L., Huang, L., Rupaimoole, R., Lopez-Casas, P. P., Pulver, E., Jeong, J. Cheol, Muthuswamy, S. K., Hidalgo, M., Bhatia, S. N., and Slack, F. J., Personalized RNA-medicine for pancreatic cancer, Clinical Cancer Research, vol. 24, no. 7, pp. 1734-1747, 2018.
N. Lippok, Villiger, M., Albanese, A., Meijer, E. F. J., Chung, K., Padera, T. P., Bhatia, S. N., and Bouma, B. E., Depolarization signatures map gold nanorods within biological tissue, Nature Photonics, vol. 11, no. 9, pp. 583-588, 2017.
E. M. Jaffee, Van Dang, C., Agus, D. B., Alexander, B. M., Anderson, K. C., Ashworth, A., Barker, A. D., Bastani, R., Bhatia, S., Bluestone, J. A., Brawley, O., Butte, A. J., Coit, D. G., Davidson, N. E., Davis, M., DePinho, R. A., Diasio, R. B., Draetta, G., A Frazier, L., Futreal, A., Gambhir, S. S., Ganz, P. A., Garraway, L., Gerson, S., Gupta, S., Heath, J., Hoffman, R. I., Hudis, C., Hughes-Halbert, C., Ibrahim, R., Jadvar, H., Kavanagh, B., Kittles, R., Le, Q. - T., Lippman, S. M., Mankoff, D., Mardis, E. R., Mayer, D. K., McMasters, K., Meropol, N. J., Mitchell, B., Naredi, P., Ornish, D., Pawlik, T. M., Peppercorn, J., Pomper, M. G., Raghavan, D., Ritchie, C., Schwarz, S. W., Sullivan, R., Wahl, R., Wolchok, J. D., Wong, S. L., and Yung, A., Future cancer research priorities in the USA: a Lancet Oncology Commission, The Lancet Oncology, vol. 18, no. 11, pp. e653 - e706, 2017.
K. R. Stevens, Scull, M. A., Ramanan, V., Fortin, C. L., Chaturvedi, R. R., Knouse, K. A., Xiao, J. W., Fung, C., Mirabella, T., Chen, A. X., McCue, M. G., Yang, M. T., Fleming, H. E., Chung, K., de Jong, Y. P., Chen, C. S., Rice, C. M., and Bhatia, S. N., In situ expansion of engineered human liver tissue in a mouse model of chronic liver disease, Science Translational Medicine, vol. 9, no. 399, 2017.
E. J. Kwon, Skalak, M., Bertucci, A., Braun, G., Ricci, F., Ruoslahti, E., Sailor, M. J., and Bhatia, S. N., Porous Silicon Nanoparticle Delivery of Tandem Peptide Anti-Infectives for the Treatment of Pseudomonas aeruginosa Lung Infections, Advanced Materials, vol. 29, no. 35, pp. 1-9, 2017.
L. T. Geller, Barzily-Rokni, M., Danino, T., Jonas, O. H., Shental, N., Nejman, D., Gavert, N., Zwang, Y., Cooper, Z. A., Shee, K., Thaiss, C. A., Reuben, A., Livny, J., Avraham, R., Frederick, D. T., Ligorio, M., Chatman, K., Johnston, S. E., Mosher, C. M., Brandis, A., Fuks, G., Gurbatri, C., Gopalakrishnan, V., Kim, M., Hurd, M. W., Katz, M., Fleming, J., Maitra, A., Smith, D. A., Skalak, M., Bu, J., Michaud, M., Trauger, S. A., Barshack, I., Golan, T., Sandbank, J., Flaherty, K. T., Mandinova, A., Garrett, W. S., Thayer, S. P., Ferrone, C. R., Huttenhower, C., Bhatia, S. N., Gevers, D., Wargo, J. A., Golub, T. R., and Straussman, R., Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine, Science, vol. 35722, no. 6356, pp. 1156 - 1160, 2017.
E. Michailidis, Pabon, J., Xiang, K., Park, P., Ramanan, V., Hoffmann, H. - H., Schneider, W. M., Bhatia, S. N., de Jong, Y. P., Shlomai, A., and Rice, C. M., A robust cell culture system supporting the complete life cycle of hepatitis B virus, Scientific Reports, vol. 7, no. 1, 2017.
S. Ng, March, S., Galstian, A., Gural, N., Stevens, K. R., Mota, M. M., and Bhatia, S. N., Towards a Humanized Mouse Model of Liver Stage Malaria Using Ectopic Artificial Livers, Scientific Reports, vol. 7, no. 45424, 2017.
Y. Ren, Sagers, J. E., Landegger, L. D., Bhatia, S. N., and Stankovic, K. M., Tumor-Penetrating Delivery of siRNA against TNFα to Human Vestibular Schwannomas, Scientific Reports, vol. 7, no. 1, 2017.
E. J. Kwon, Dudani, J. S. , and Bhatia, S. N., Ultrasensitive tumour-penetrating nanosensors of protease activity, Nature Biomedical Engineering, vol. 1, p. 0054, 2017.
J. H. Lo, Kwon, E. J. , Zhang, A. Q., Singhal, P., and Bhatia, S. N., Comparison of Modular PEG Incorporation Strategies for Stabilization of Peptide–siRNA Nanocomplexes, Bioconjugate Chemistry, vol. 27, no. 10, pp. 2323-2331, 2016.
P. K. Jain, Ramanan, V., Schepers, A. G., Dalvie, N. S., Panda, A., Fleming, H. E., and Bhatia, S. N., Development of Light-Activated CRISPR Using Guide RNAs with Photocleavable Protectors, Angewandte Chemie International Edition, vol. 55, no. 40, pp. 12440–12444, 2016.
N. Kato, Comer, E., Sakata-Kato, T., Sharma, A., Sharma, M., Maetani, M., Bastien, J., Brancucci, N. M., Bittker, J. A., Corey, V., Clarke, D., Derbyshire, E. R., Dornan, G., Duffy, S., Eckley, S., Itoe, M. A., Koolen, K. M. J., Lewis, T. A., Lui, P. S., Lukens, A. K., Lund, E., March, S., Meibalan, E., Meier, B. C., McPhail, J., Mitasev, B., Moss, E. L., Sayes, M., VanGessel, Y., Wawer, M. J., Yoshinaga, T., Zeeman, A. - M., Avery, V. M., Bhatia, S. N., Burke, J. E., Catteruccia, F., Clardy, J. C., Clemons, P. A., Dechering, K. J., Duvall, J. R., Foley, M. A., Gusovsky, F., Kocken, C. H. M., Marti, M., Morningstar, M. L., Munoz, B., Neafsey, D. E., Sharma, A., Winzeler, E. A., Wirth, D. F., Scherer, C. A., and Schreiber, S. L., Diversity-oriented synthesis yields novel multistage antimalarial inhibitors, Nature, vol. 538, no. 7625, pp. 344-349, 2016.
A. Schepers, Li, C., Chhabra, A., Seney, B. Tschudy, and Bhatia, S., Engineering a perfusable 3D human liver platform from iPS cells, Lab Chip, vol. 16, pp. 2644-2653, 2016.
D. F. Braga Malta, Reticker-Flynn, N. E., da Silva, C. L., Cabral, J. M. S., Fleming, H. E., Zaret, K. S., Bhatia, S. N., and Underhill, G. H., Extracellular matrix microarrays to study inductive signaling for endoderm specification., Acta Biomater, vol. 34, pp. 30-40, 2016.
J. Shan, Logan, D. J., Root, D. E., Carpenter, A. E., and Bhatia, S. N., High-Throughput Platform for Identifying Molecular Factors Involved in Phenotypic Stabilization of Primary Human Hepatocytes In Vitro, Journal of Biomolecular Screening, pp. 1-15, 2016.
M. T. Grilo Ruivo, Vera, I. Medina, Sales-Dias, J., Meireles, P., Gural, N., Bhatia, S. N., Mota, M. M., and Mancio-Silva, L., Host AMPK Is a Modulator of Plasmodium Liver Infection., Cell Rep, vol. 16, no. 10, pp. 2539-45, 2016.
K. Shaw-Saliba, Clarke, D., Santos, J. M., Menezes, M. José, Lim, C., Mascarenhas, A., Chery, L., Gomes, E., March, S., Bhatia, S. N., Rathod, P. K., Ferreira, M. U., Catteruccia, F., and Duraisingh, M. T., Infection of laboratory colonies of Anopheles mosquitoes with Plasmodium vivax from cryopreserved clinical isolates., Int J Parasitol, vol. 46, no. 11, pp. 679-683, 2016.
S. Schuerle, Dudani, J. S. , Christiansen, M. G., Anikeeva, P., and Bhatia, S. N., Magnetically Actuated Protease Sensors for in Vivo Tumor Profiling, Nano Letters, vol. 16, no. 10, pp. 6303–6310, 2016.
E. J. Kwon, Skalak, M., Bu, R. Lo, and Bhatia, S. N., Neuron-Targeted Nanoparticle for siRNA Delivery to Traumatic Brain Injuries, ACS Nano, vol. 10, no. 8, pp. 7926–7933, 2016.
W. C. Van Voorhis, Adams, J. H., Adelfio, R., Ahyong, V., Akabas, M. H., Alano, P., Alday, A., Resto, Yán, Alsibaee, A., Alzualde, A., Andrews, K. T., Avery, S. V., Avery, V. M., Ayong, L., Baker, M., Baker, S., Ben Mamoun, C., Bhatia, S., Bickle, Q., Bounaadja, L., Bowling, T., Bosch, ürgen, Boucher, L. E., Boyom, F. F., Brea, J., Brennan, M., Burton, A., Caffrey, C. R., Camarda, G., Carrasquilla, M., Carter, D., Cassera, M. Belen, Cheng, K. Chih- Chien, Chindaudomsate, W., Chubb, A., Colon, B. L., n-López, D. D. ó, Corbett, Y., Crowther, G. J., Cowan, N., Alessandro, S. ’, Le Dang, N., Delves, M., DeRisi, J. L., Du, A. Y., Duffy, S., El-Sayed, S. Abd El- Sal, Ferdig, M. T., Robledo, éA. ández, Fidock, D. A., Florent, I., Fokou, P. V. T., Galstian, A., Gamo, F. Javier, Gokool, S., Gold, B., Golub, T., Goldgof, G. M., Guha, R., W. Guiguemde, A., Gural, N., R. Guy, K., Hansen, M. A. E., Hanson, K. K., Hemphill, A., van Huijsduijnen, R. Hooft, Horii, T., Horrocks, P., Hughes, T. B., Huston, C., Igarashi, I., Ingram-Sieber, K., Itoe, M. A., Jadhav, A., Jensen, A. Naranuntar, Jensen, L. T., Jiang, R. H. Y., Kaiser, A., Keiser, J., Ketas, T., Kicka, S., Kim, S., Kirk, K., Kumar, V. P., Kyle, D. E., Lafuente, M. Jose, Landfear, S., Lee, N., Lee, S., Lehane, A. M., Li, F., Little, D., Liu, L., s, Má, Loza, M. I., Lubar, A., Lucantoni, L., Lucet, I., Maes, L., Mancama, D., Mansour, N. R., March, S., McGowan, S., Vera, I. Medina, Meister, S., Mercer, L., Mestres, J., Mfopa, A. N., Misra, R. N., Moon, S., Moore, J. P., da Costa, F. Morais Rod, ller, Jü, Muriana, A., Hewitt, S. Nakazawa, Nare, B., Nathan, C., Narraidoo, N., Nawaratna, S., Ojo, K. K., Ortiz, D., Panic, G., Papadatos, G., Parapini, S., Patra, K., Pham, N., Prats, S., Plouffe, D. M., Poulsen, S. - A., Pradhan, A., Quevedo, C., Quinn, R. J., Rice, C. A., Rizk, M. Abdo, Ruecker, A., Onge, R. St., Ferreira, R. Salgado, Samra, J., Robinett, N. G., Schlecht, U., Schmitt, M., Villela, F. Silva, Silvestrini, F., Sinden, R., Smith, D. A., Soldati, T., ller, Aü, Stamm, S. Maximilian, Sullivan, D. J., Sullivan, W., Suresh, S., Suzuki, B. M., Suzuki, Y., S. Swamidass, J., Taramelli, D., Tchokouaha, L. R. Y., Theron, A., Thomas, D., Tonissen, K. F., Townson, S., Tripathi, A. K., Trofimov, V., Udenze, K. O., Ullah, I., Vallieres, C., Vigil, E., Vinetz, J. M., Vinh, P. Voong, Vu, H., Watanabe, N. -aki, Weatherby, K., White, P. M., Wilks, A. F., Winzeler, E. A., Wojcik, E., Wree, M., Wu, W., Yokoyama, N., Zollo, P. H. A., Abla, N., Blasco, B., Burrows, J., Laleu, ît, Leroy, D., Spangenberg, T., Wells, T., and Willis, P. A., Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond, PLOS Pathogens, vol. 12, no. 7, 2016.