Found 223 results
A. P. Soleimany and Bhatia, S. N., Activity-Based Diagnostics: An Emerging Paradigm for Disease Detection and Monitoring, Trends in Molecular Medicine, 2020.
C. Tian, hlund, D. Ö., Rickelt, S., m, Tö, Huang, Y., Hao, L., Zhao, R. T., Franklin, O., Bhatia, S. N., Tuveson, D. A., and Hynes, R. O., Cancer Cell–Derived Matrisome Proteins Promote Metastasis in Pancreatic Ductal Adenocarcinoma, Cancer Research, vol. 80, no. 7, pp. 1461 - 1474, 2020.
A. X. Chen, Chhabra, A., Song, ‐H. Greco, Fleming, H. E., Chen, C. S., and Bhatia, S. N., Controlled Apoptosis of Stromal Cells to Engineer Human Microlivers, Advanced Functional Materials, vol. 60, 2020.
L. Hao, Zhao, R. T., Ngambenjawong, C., Fleming, H. E., and Bhatia, S. N., CRISPR-Cas-amplified urine biomarkers for multiplexed and portable cancer diagnostics, bioRxiv, 2020.
E. Michailidis, Vercauteren, K., Mancio-Silva, L., Andrus, L., Jahan, C., Ricardo-Lax, I., Zou, C., Kabbani, M., Park, P., Quirk, C., Pyrgaki, C., Razooky, B., Verhoye, L., Zoluthkin, I., Lu, W. - Y., Forbes, S. J., Chiriboga, L., Theise, N. D., Herzog, R. W., Suemizu, H., Schneider, W. M., Shlomai, A., Meuleman, P., Bhatia, S. N., Rice, C. M., and de Jong, Y. P., Expansion, in vivo–ex vivo cycling, and genetic manipulation of primary human hepatocytes, Proceedings of the National Academy of Sciences, vol. 117, no. 3, pp. 1678 - 1688, 2020.
S. Schuerle, Furubayashi, M., Soleimany, A. P., Gwisai, T., Huang, W., Voigt, C., and Bhatia, S. N., Genetic Encoding of Targeted Magnetic Resonance Imaging Contrast Agents for Tumor Imaging, ACS Synthetic Biology, 2020.
C. G. Buss and Bhatia, S. N., Nanoparticle delivery of immunostimulatory oligonucleotides enhances response to checkpoint inhibitor therapeutics, Proceedings of the National Academy of Sciences, 2020.
N. K. Mehta, Pradhan, R. V., Soleimany, A. P., Moynihan, K. D., Rothschilds, A. M., Momin, N., Rakhra, K., Mata-Fink, J., Bhatia, S. N., K. Wittrup, D., and Irvine, D. J., Pharmacokinetic tuning of protein–antigen fusions enhances the immunogenicity of T-cell vaccines, Nature Biomedical Engineering, 2020.
P. Nair, QnAs with Sangeeta N. Bhatia, Proceedings of the National Academy of Sciences, p. 201922176, 2020.
J. D. Kirkpatrick, Warren, A. D. , Soleimany, A. P. , Westcott, P. M. K., Voog, J. C., Martin-Alonso, C., Fleming, H. E., Tammela, T., Jacks, T., and Bhatia, S. N., Urinary detection of lung cancer in mice via noninvasive pulmonary protease profiling, Science Translational Medicine, vol. 12, no. 537, p. eaaw0262, 2020.
N. Rohani, Hao, L., Alexis, M. S., Joughin, B. A., Krismer, K., Moufarrej, M. N., Soltis, A. R., Lauffenburger, D. A., Yaffe, M. B., Burge, C. B., Bhatia, S. N., and Gertler, F. B., Acidification of tumor at stromal boundaries drives transcriptome alterations associated with aggressive phenotypes, Cancer Research, 2019.
G. Camarda, Jirawatcharadech, P., Priestley, R. S., Saif, A., March, S., Wong, M. H. L., Leung, S., Miller, A. B., Baker, D. A., Alano, P., Paine, M. J. I., Bhatia, S. N., Neill, P. M. ’, Ward, S. A., and Biagini, G. A., Antimalarial activity of primaquine operates via a two-step biochemical relay, Nature Communications, vol. 10, no. 3226, 2019.
S. Chaturantabut, Shwartz, A., Evason, K. J., Cox, A. G., Labella, K., Schepers, A. G., Yang, S., Aravena, M., Houvras, iv, Y., Mancio-Silva, L., Romano, S., Gorelick, D. A., Cohen, D. E., Zon, L. I., Bhatia, S. N., North, T. E., and Goessling, W., Estrogen Activation of G protein-coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes, Gastroenterology, 2019.
L. Mancio-Silva, Fleming, H. E., Miller, A. B., Milstein, S., Liebow, A., Haslett, P., Sepp-Lorenzino, L., and Bhatia, S. N., Improving Drug Discovery by Nucleic Acid Delivery in Engineered Human Microlivers, Cell Metabolism, vol. 29, no. 3, pp. 727 - 735.e3, 2019.
P. K. Jain, Lo, J. H., Rananaware, S., Downing, M., Panda, A., Tai, M., Raghavan, S., Fleming, H. E., and Bhatia, S. N. , Non-viral delivery of CRISPR/Cas9 complex using CRISPR-GPS nanocomplexes, Nanoscale, vol. 11, no. 441, pp. 21317 - 21323, 2019.
C. N. Loynachan, Soleimany, A. P. , Dudani, J. S., Lin, Y., Najer, A., Bekdemir, A., Chen, Q., Bhatia, S. N. , and Stevens, M. M. , Renal clearable catalytic gold nanoclusters for in vivo disease monitoring, Nature Nanotechnology, 2019.
K. Werling, W. Shaw, R., Itoe, M. A., Westervelt, K. A., Marcenac, P., Paton, D. G., Peng, D., Singh, N., Smidler, A. L., South, A., Deik, A. A., Mancio-Silva, L., Demas, A. R., March, S., Calvo, E., Bhatia, S. N., Clish, C. B., and Catteruccia, F., Steroid Hormone Function Controls Non-competitive Plasmodium Development in Anopheles, Cell, vol. 177, no. 2, pp. 315 - 325.e14, 2019.
S. Schuerle, Soleimany, A. P., Yeh, T., Anand, G. M., berli, Mä, Fleming, H. E., Mirkhani, N., Qiu, F., Hauert, S., Wang, X., Nelson, B. J., and Bhatia, S. N., Synthetic and living micropropellers for convection-enhanced nanoparticle transport, Science Advances, vol. 5, no. 4, p. eaav4803, 2019.
I. Medina Vera, Ruivo, M. T. Grilo, Rocha, L. F. Lemos, Marques, S., Bhatia, S. N., Mota, M. M., and Mancio-Silva, L., Targeting liver stage malaria with metformin, JCI Insight, vol. 4, no. 24, 2019.
N. Boehnke, Correa, S. , Hao, L. , Wang, W., Straehla, J. P., Bhatia, S. N., and Hammond, P., Theranostic Layer-by-Layer Nanoparticles for Simultaneous Tumor Detection and Gene Silencing, Angewandte Chemie International Edition, 2019.
M. - E. Gilles, Hao, L., Brown, K., Lim, J., Bhatia, S. N., and Slack, F. J., Tumor penetrating nanomedicine targeting both an oncomiR and an oncogene in pancreatic cancer, Oncotarget, vol. 10, no. 51, 2019.
A. Amini, Soleimany, A. , Schwarting, W., Bhatia, S. N., and Rus, D., Uncovering and Mitigating Algorithmic Bias through Learned Latent Structure, AAAI/ACM Conference on Artificial Intelligence, Ethics, and Society, 2019.