Found 37 results
Filters: Author is Bhatia, Sangeeta N.  [Clear All Filters]
N. Rohani, Hao, L., Alexis, M. S., Joughin, B. A., Krismer, K., Moufarrej, M. N., Soltis, A. R., Lauffenburger, D. A., Yaffe, M. B., Burge, C. B., Bhatia, S. N., and Gertler, F. B., Acidification of tumor at stromal boundaries drives transcriptome alterations associated with aggressive phenotypes, Cancer Research, 2019.
S. Chaturantabut, Shwartz, A., Evason, K. J., Cox, A. G., Labella, K., Schepers, A. G., Yang, S., Aravena, M., Houvras, iv, Y., Mancio-Silva, L., Romano, S., Gorelick, D. A., Cohen, D. E., Zon, L. I., Bhatia, S. N., North, T. E., and Goessling, W., Estrogen Activation of G protein-coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes, Gastroenterology, 2019.
L. Mancio-Silva, Fleming, H. E., Miller, A. B., Milstein, S., Liebow, A., Haslett, P., Sepp-Lorenzino, L., and Bhatia, S. N., Improving Drug Discovery by Nucleic Acid Delivery in Engineered Human Microlivers, Cell Metabolism, vol. 29, no. 3, pp. 727 - 735.e3, 2019.
K. Werling, W. Shaw, R., Itoe, M. A., Westervelt, K. A., Marcenac, P., Paton, D. G., Peng, D., Singh, N., Smidler, A. L., South, A., Deik, A. A., Mancio-Silva, L., Demas, A. R., March, S., Calvo, E., Bhatia, S. N., Clish, C. B., and Catteruccia, F., Steroid Hormone Function Controls Non-competitive Plasmodium Development in Anopheles, Cell, vol. 177, no. 2, pp. 315 - 325.e14, 2019.
N. Boehnke, Correa, S. , Hao, L. , Wang, W., Straehla, J. P., Bhatia, S. N., and Hammond, P., Theranostic Layer-by-Layer Nanoparticles for Simultaneous Tumor Detection and Gene Silencing, Angewandte Chemie International Edition, 2019.
M. - E. Gilles, Hao, L., Brown, K., Lim, J., Bhatia, S. N., and Slack, F. J., Tumor penetrating nanomedicine targeting both an oncomiR and an oncogene in pancreatic cancer, Oncotarget, vol. 10, no. 51, 2019.
A. Amini, Soleimany, A. , Schwarting, W., Bhatia, S. N., and Rus, D., Uncovering and Mitigating Algorithmic Bias through Learned Latent Structure, AAAI/ACM Conference on Artificial Intelligence, Ethics, and Society, 2019.
N. Gural, Mancio-Silva, L., He, J., and Bhatia, S. N., Engineered Livers for Infectious Diseases, Cellular and Molecular Gastroenterology and Hepatology, vol. 5, no. 2, pp. 131 - 144, 2018.
S. R. Viswanathan, Nogueira, M. F., Buss, C. G., Krill-Burger, J. M., Wawer, M. J., Malolepsza, E., Berger, A. C., Choi, P. S., Shih, J., Taylor, A. M., Tanenbaum, B., Pedamallu, C. Sekhar, Cherniack, A. D., Tamayo, P., Strathdee, C. A., Lage, K., Carr, S. A., Schenone, M., Bhatia, S. N., Vazquez, F., Tsherniak, A., Hahn, W. C., and Meyerson, M., Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer, Nature Genetics, vol. 50, no. 7, pp. 937 - 943, 2018.
J. S. Dudani, Warren, A. D., and Bhatia, S. N., Harnessing Protease Activity to Improve Cancer Care, Annual Review of Cancer Biology, vol. 2, no. 1, 2018.
N. K. Kisalu, Idris, A. H. , Weidle, C., Flores-Garcia, Y., Flynn, B. J., Sack, B. K., Murphy, S., Schön, A., Freire, E., Francica, J. R., Miller, A. B., Gregory, J., March, S., Liao, H. - X., Haynes, B. F., Wiehe, K., Trama, A. M., Saunders, K. O., Gladden, M. A., Monroe, A., Bonsignori, M., Kanekiyo, M., Wheatley, A. K., McDermott, A. B., S Farney, K., Chuang, G. - Y., Zhang, B., Kc, N., Chakravarty, S., Kwong, P. D., Sinnis, P., Bhatia, S. N., Kappe, S. H. I., B Sim, K. Lee, Hoffman, S. L., Zavala, F., Pancera, M. , and Seder, R. A. ‡<, A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite, Nature Medicine, vol. 24, no. 4, pp. 408-416, 2018.
N. Gural, Mancio-Silva, L., Miller, A. B., Galstian, A., Butty, V. L., Levine, S. S., Patrapuvich, R., Desai, S. P., Mikolajczak, S. A., Kappe, S. H. I., Fleming, H. E., March, S., Sattabongkot, J., and Bhatia, S. N., In Vitro Culture, Drug Sensitivity, and Transcriptome of Plasmodium Vivax Hypnozoites, Cell Host & Microbe, vol. 23, no. 3, pp. 395-406, 2018.
J. H. Lo, Hao, L. , Muzumdar, M. D., Raghavan, S., Kwon, E. J., Pulver, E. M., Hsu, F., Aguirre, A. J., Wolpin, B. M., Fuchs, C. S., Hahn, W. C., Jacks, T., and Bhatia, S. N., iRGD-guided tumor-penetrating nanocomplexes for therapeutic siRNA delivery to pancreatic cancer, Molecular Cancer Therapeutics, vol. 17, no. 11, pp. 2377-2388, 2018.
M. - E. Gilles, Hao, L., Huang, L., Rupaimoole, R., Lopez-Casas, P. P., Pulver, E., Jeong, J. Cheol, Muthuswamy, S. K., Hidalgo, M., Bhatia, S. N., and Slack, F. J., Personalized RNA-medicine for pancreatic cancer, Clinical Cancer Research, vol. 24, no. 7, pp. 1734-1747, 2018.
A. M. Mendes, Machado, M., alves-Rosa, Nç, Reuling, I. J., Foquet, L., Marques, áudia, Salman, A. M., Yang, A. S. P., Moser, K. A., Dwivedi, A., Hermsen, C. C., nez-Díaz, éné, Viera, S., Santos, J. M., Albuquerque, ês, Bhatia, S. N., Bial, J., Angulo-Barturen, ñigo, Silva, J. C., Leroux-Roels, G., Janse, C. J., Khan, S. M., Mota, M. M., Sauerwein, R. W., and Prudêncio, M., A Plasmodium berghei sporozoite-based vaccination platform against human malaria, npj Vaccines, vol. 3, 2018.
C. G. Buss, Dudani, J. S. , Akana, R. T. K., Fleming, H. E., and Bhatia, S. N., Protease activity sensors noninvasively classify bacterial infections and antibiotic responses, EBioMedicine, vol. 38, pp. 248-256, 2018.
N. Lippok, Villiger, M., Albanese, A., Meijer, E. F. J., Chung, K., Padera, T. P., Bhatia, S. N., and Bouma, B. E., Depolarization signatures map gold nanorods within biological tissue, Nature Photonics, vol. 11, no. 9, pp. 583-588, 2017.
K. R. Stevens, Scull, M. A., Ramanan, V., Fortin, C. L., Chaturvedi, R. R., Knouse, K. A., Xiao, J. W., Fung, C., Mirabella, T., Chen, A. X., McCue, M. G., Yang, M. T., Fleming, H. E., Chung, K., de Jong, Y. P., Chen, C. S., Rice, C. M., and Bhatia, S. N., In situ expansion of engineered human liver tissue in a mouse model of chronic liver disease, Science Translational Medicine, vol. 9, no. 399, 2017.
E. J. Kwon, Skalak, M., Bertucci, A., Braun, G., Ricci, F., Ruoslahti, E., Sailor, M. J., and Bhatia, S. N., Porous Silicon Nanoparticle Delivery of Tandem Peptide Anti-Infectives for the Treatment of Pseudomonas aeruginosa Lung Infections, Advanced Materials, vol. 29, no. 35, pp. 1-9, 2017.
L. T. Geller, Barzily-Rokni, M. , Danino, T., Jonas, O. H., Shental, N., Nejman, D., Gavert, N., Zwang, Y., Cooper, Z. A., Shee, K., Thaiss, C. A., Reuben, A., Livny, J., Avraham, R., Frederick, D. T., Ligorio, M., Chatman, K., Johnston, S. E., Mosher, C. M., Brandis, A., Fuks, G., Gurbatri, C., Gopalakrishnan, V., Kim, M., Hurd, M. W., Katz, M., Fleming, J., Maitra, A., Smith, D. A., Skalak, M., Bu, J., Michaud, M., Trauger, S. A., Barshack, I., Golan, T., Sandbank, J., Flaherty, K. T., Mandinova, A., Garrett, W. S., Thayer, S. P., Ferrone, C. R., Huttenhower, C., Bhatia, S. N., Gevers, D., Wargo, J. A., Golub, T. R., and Straussman, R., Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine, Science, vol. 35722, no. 6356, pp. 1156 - 1160, 2017.
E. Michailidis, Pabon, J., Xiang, K., Park, P., Ramanan, V., Hoffmann, H. - H., Schneider, W. M., Bhatia, S. N., de Jong, Y. P., Shlomai, A., and Rice, C. M., A robust cell culture system supporting the complete life cycle of hepatitis B virus, Scientific Reports, vol. 7, no. 1, 2017.