Found 232 results
A. P. Soleimany, Kirkpatrick, J. D. , Su, S., Dudani, J. S., Zhong, Q., Bekdemir, A., and Bhatia, S. N., Activatable zymography probes enable in situ localization of protease dysregulation in cancer, Cancer Research, vol. 81, no. 1, pp. 213-224, 2020.
A. P. Soleimany and Bhatia, S. N., Activity-Based Diagnostics: An Emerging Paradigm for Disease Detection and Monitoring, Trends in Molecular Medicine, 2020.
C. Tian, hlund, D. Ö., Rickelt, S., m, Tö, Huang, Y., Hao, L., Zhao, R. T., Franklin, O., Bhatia, S. N., Tuveson, D. A., and Hynes, R. O., Cancer Cell–Derived Matrisome Proteins Promote Metastasis in Pancreatic Ductal Adenocarcinoma, Cancer Research, vol. 80, no. 7, pp. 1461 - 1474, 2020.
A. X. Chen, Chhabra, A., Song, ‐H. Greco, Fleming, H. E., Chen, C. S., and Bhatia, S. N., Controlled Apoptosis of Stromal Cells to Engineer Human Microlivers, Advanced Functional Materials, vol. 60, 2020.
L. Hao, Zhao, R. T., Ngambenjawong, C., Fleming, H. E., and Bhatia, S. N., CRISPR-Cas-amplified urine biomarkers for multiplexed and portable cancer diagnostics, bioRxiv, 2020.
L. W. Chan, Anahtar, M. N., Ong, T. - H., Hern, K. E., Kunz, R. R., and Bhatia, S. N., Engineering synthetic breath biomarkers for respiratory disease, Nature Nanotechnology, 2020.
E. Michailidis, Vercauteren, K., Mancio-Silva, L., Andrus, L., Jahan, C., Ricardo-Lax, I., Zou, C., Kabbani, M., Park, P., Quirk, C., Pyrgaki, C., Razooky, B., Verhoye, L., Zoluthkin, I., Lu, W. - Y., Forbes, S. J., Chiriboga, L., Theise, N. D., Herzog, R. W., Suemizu, H., Schneider, W. M., Shlomai, A., Meuleman, P., Bhatia, S. N., Rice, C. M., and de Jong, Y. P., Expansion, in vivo–ex vivo cycling, and genetic manipulation of primary human hepatocytes, Proceedings of the National Academy of Sciences, vol. 117, no. 3, pp. 1678 - 1688, 2020.
S. Schuerle, Furubayashi, M., Soleimany, A. P., Gwisai, T., Huang, W., Voigt, C., and Bhatia, S. N., Genetic Encoding of Targeted Magnetic Resonance Imaging Contrast Agents for Tumor Imaging, ACS Synthetic Biology, 2020.
T. J. Suscovich, Fallon, J. K., Das, J., Demas, A. R., Crain, J., Linde, C. H., Michell, A., Natarajan, H., Arevalo, C., Broge, T., Linnekin, T., Kulkarni, V., Lu, R., Slein, M. D., Luedemann, C., Marquette, M., March, S., Weiner, J., Gregory, S., Coccia, M., Flores-Garcia, Y., Zavala, F., Ackerman, M. E., Bergmann-Leitner, E., Hendriks, J., Sadoff, J., Dutta, S., Bhatia, S. N., Lauffenburger, D. A., Jongert, E., Wille-Reece, U., and Alter, G., Mapping functional humoral correlates of protection against malaria challenge following RTS,S/AS01 vaccination, Science Translational Medicine, vol. 12, no. 553, p. eabb4757, 2020.
C. G. Buss and Bhatia, S. N., Nanoparticle delivery of immunostimulatory oligonucleotides enhances response to checkpoint inhibitor therapeutics, Proceedings of the National Academy of Sciences, 2020.
E. J. Kwon, Ko, H., and Bhatia, S. N., Peptide Spiders: Peptide–Polymer Conjugates to Traffic Nucleic AcidsPeptide Spiders: PeptidePolymer Conjugates to Traffic Nucleic Acids, Molecular Pharmaceutics, 2020.
N. K. Mehta, Pradhan, R. V., Soleimany, A. P., Moynihan, K. D., Rothschilds, A. M., Momin, N., Rakhra, K., Mata-Fink, J., Bhatia, S. N., K. Wittrup, D., and Irvine, D. J., Pharmacokinetic tuning of protein–antigen fusions enhances the immunogenicity of T-cell vaccines, Nature Biomedical Engineering, 2020.
P. Nair, QnAs with Sangeeta N. Bhatia, Proceedings of the National Academy of Sciences, p. 201922176, 2020.
G. Song, Lammers, A., Sundaram, S., Rubio, L., Chen, A. X., Li, L., Eyckmans, J., Bhatia, S. N., and Chen, C. S., Transient Support from Fibroblasts is Sufficient to Drive Functional Vascularization in Engineered Tissues, Advanced Functional Materials, vol. 30, no. 48, p. 2003777, 2020.
J. D. Kirkpatrick, Warren, A. D. , Soleimany, A. P. , Westcott, P. M. K., Voog, J. C., Martin-Alonso, C., Fleming, H. E., Tammela, T., Jacks, T., and Bhatia, S. N., Urinary detection of lung cancer in mice via noninvasive pulmonary protease profiling, Science Translational Medicine, vol. 12, no. 537, p. eaaw0262, 2020.
N. Rohani, Hao, L., Alexis, M. S., Joughin, B. A., Krismer, K., Moufarrej, M. N., Soltis, A. R., Lauffenburger, D. A., Yaffe, M. B., Burge, C. B., Bhatia, S. N., and Gertler, F. B., Acidification of tumor at stromal boundaries drives transcriptome alterations associated with aggressive phenotypes, Cancer Research, 2019.
G. Camarda, Jirawatcharadech, P., Priestley, R. S., Saif, A., March, S., Wong, M. H. L., Leung, S., Miller, A. B., Baker, D. A., Alano, P., Paine, M. J. I., Bhatia, S. N., Neill, P. M. ’, Ward, S. A., and Biagini, G. A., Antimalarial activity of primaquine operates via a two-step biochemical relay, Nature Communications, vol. 10, no. 3226, 2019.
S. Chaturantabut, Shwartz, A., Evason, K. J., Cox, A. G., Labella, K., Schepers, A. G., Yang, S., Aravena, M., Houvras, iv, Y., Mancio-Silva, L., Romano, S., Gorelick, D. A., Cohen, D. E., Zon, L. I., Bhatia, S. N., North, T. E., and Goessling, W., Estrogen Activation of G protein-coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes, Gastroenterology, 2019.
L. Mancio-Silva, Fleming, H. E., Miller, A. B., Milstein, S., Liebow, A., Haslett, P., Sepp-Lorenzino, L., and Bhatia, S. N., Improving Drug Discovery by Nucleic Acid Delivery in Engineered Human Microlivers, Cell Metabolism, vol. 29, no. 3, pp. 727 - 735.e3, 2019.
P. K. Jain, Lo, J. H., Rananaware, S., Downing, M., Panda, A., Tai, M., Raghavan, S., Fleming, H. E., and Bhatia, S. N. , Non-viral delivery of CRISPR/Cas9 complex using CRISPR-GPS nanocomplexes, Nanoscale, vol. 11, no. 441, pp. 21317 - 21323, 2019.
C. N. Loynachan, Soleimany, A. P. , Dudani, J. S., Lin, Y., Najer, A., Bekdemir, A., Chen, Q., Bhatia, S. N. , and Stevens, M. M. , Renal clearable catalytic gold nanoclusters for in vivo disease monitoring, Nature Nanotechnology, 2019.