Found 50 results
Filters: Author is Bhatia, Sangeeta N.  [Clear All Filters]
A. P. Soleimany and Bhatia, S. N., Activity-Based Diagnostics: An Emerging Paradigm for Disease Detection and Monitoring, Trends in Molecular Medicine, 2020.
C. Tian, hlund, D. Ö., Rickelt, S., m, Tö, Huang, Y., Hao, L., Zhao, R. T., Franklin, O., Bhatia, S. N., Tuveson, D. A., and Hynes, R. O., Cancer Cell–Derived Matrisome Proteins Promote Metastasis in Pancreatic Ductal Adenocarcinoma, Cancer Research, vol. 80, no. 7, pp. 1461 - 1474, 2020.
A. X. Chen, Chhabra, A., Song, ‐H. Greco, Fleming, H. E., Chen, C. S., and Bhatia, S. N., Controlled Apoptosis of Stromal Cells to Engineer Human Microlivers, Advanced Functional Materials, vol. 60, 2020.
L. Hao, Zhao, R. T., Ngambenjawong, C., Fleming, H. E., and Bhatia, S. N., CRISPR-Cas-amplified urine biomarkers for multiplexed and portable cancer diagnostics, bioRxiv, 2020.
L. W. Chan, Anahtar, M. N., Ong, T. - H., Hern, K. E., Kunz, R. R., and Bhatia, S. N., Engineering synthetic breath biomarkers for respiratory disease, Nature Nanotechnology, 2020.
E. Michailidis, Vercauteren, K., Mancio-Silva, L., Andrus, L., Jahan, C., Ricardo-Lax, I., Zou, C., Kabbani, M., Park, P., Quirk, C., Pyrgaki, C., Razooky, B., Verhoye, L., Zoluthkin, I., Lu, W. - Y., Forbes, S. J., Chiriboga, L., Theise, N. D., Herzog, R. W., Suemizu, H., Schneider, W. M., Shlomai, A., Meuleman, P., Bhatia, S. N., Rice, C. M., and de Jong, Y. P., Expansion, in vivo–ex vivo cycling, and genetic manipulation of primary human hepatocytes, Proceedings of the National Academy of Sciences, vol. 117, no. 3, pp. 1678 - 1688, 2020.
S. Schuerle, Furubayashi, M., Soleimany, A. P., Gwisai, T., Huang, W., Voigt, C., and Bhatia, S. N., Genetic Encoding of Targeted Magnetic Resonance Imaging Contrast Agents for Tumor Imaging, ACS Synthetic Biology, 2020.
T. J. Suscovich, Fallon, J. K., Das, J., Demas, A. R., Crain, J., Linde, C. H., Michell, A., Natarajan, H., Arevalo, C., Broge, T., Linnekin, T., Kulkarni, V., Lu, R., Slein, M. D., Luedemann, C., Marquette, M., March, S., Weiner, J., Gregory, S., Coccia, M., Flores-Garcia, Y., Zavala, F., Ackerman, M. E., Bergmann-Leitner, E., Hendriks, J., Sadoff, J., Dutta, S., Bhatia, S. N., Lauffenburger, D. A., Jongert, E., Wille-Reece, U., and Alter, G., Mapping functional humoral correlates of protection against malaria challenge following RTS,S/AS01 vaccination, Science Translational Medicine, vol. 12, no. 553, p. eabb4757, 2020.
C. G. Buss and Bhatia, S. N., Nanoparticle delivery of immunostimulatory oligonucleotides enhances response to checkpoint inhibitor therapeutics, Proceedings of the National Academy of Sciences, 2020.
E. J. Kwon, Ko, H., and Bhatia, S. N., Peptide Spiders: Peptide–Polymer Conjugates to Traffic Nucleic AcidsPeptide Spiders: PeptidePolymer Conjugates to Traffic Nucleic Acids, Molecular Pharmaceutics, 2020.
N. K. Mehta, Pradhan, R. V., Soleimany, A. P., Moynihan, K. D., Rothschilds, A. M., Momin, N., Rakhra, K., Mata-Fink, J., Bhatia, S. N., K. Wittrup, D., and Irvine, D. J., Pharmacokinetic tuning of protein–antigen fusions enhances the immunogenicity of T-cell vaccines, Nature Biomedical Engineering, 2020.
G. Song, Lammers, A., Sundaram, S., Rubio, L., Chen, A. X., Li, L., Eyckmans, J., Bhatia, S. N., and Chen, C. S., Transient Support from Fibroblasts is Sufficient to Drive Functional Vascularization in Engineered Tissues, Advanced Functional Materials, vol. 30, no. 48, p. 2003777, 2020.
J. D. Kirkpatrick, Warren, A. D. , Soleimany, A. P. , Westcott, P. M. K., Voog, J. C., Martin-Alonso, C., Fleming, H. E., Tammela, T., Jacks, T., and Bhatia, S. N., Urinary detection of lung cancer in mice via noninvasive pulmonary protease profiling, Science Translational Medicine, vol. 12, no. 537, p. eaaw0262, 2020.
N. Rohani, Hao, L., Alexis, M. S., Joughin, B. A., Krismer, K., Moufarrej, M. N., Soltis, A. R., Lauffenburger, D. A., Yaffe, M. B., Burge, C. B., Bhatia, S. N., and Gertler, F. B., Acidification of tumor at stromal boundaries drives transcriptome alterations associated with aggressive phenotypes, Cancer Research, 2019.
G. Camarda, Jirawatcharadech, P., Priestley, R. S., Saif, A., March, S., Wong, M. H. L., Leung, S., Miller, A. B., Baker, D. A., Alano, P., Paine, M. J. I., Bhatia, S. N., Neill, P. M. ’, Ward, S. A., and Biagini, G. A., Antimalarial activity of primaquine operates via a two-step biochemical relay, Nature Communications, vol. 10, no. 3226, 2019.
S. Chaturantabut, Shwartz, A., Evason, K. J., Cox, A. G., Labella, K., Schepers, A. G., Yang, S., Aravena, M., Houvras, iv, Y., Mancio-Silva, L., Romano, S., Gorelick, D. A., Cohen, D. E., Zon, L. I., Bhatia, S. N., North, T. E., and Goessling, W., Estrogen Activation of G protein-coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes, Gastroenterology, 2019.
L. Mancio-Silva, Fleming, H. E., Miller, A. B., Milstein, S., Liebow, A., Haslett, P., Sepp-Lorenzino, L., and Bhatia, S. N., Improving Drug Discovery by Nucleic Acid Delivery in Engineered Human Microlivers, Cell Metabolism, vol. 29, no. 3, pp. 727 - 735.e3, 2019.
K. Werling, W. Shaw, R., Itoe, M. A., Westervelt, K. A., Marcenac, P., Paton, D. G., Peng, D., Singh, N., Smidler, A. L., South, A., Deik, A. A., Mancio-Silva, L., Demas, A. R., March, S., Calvo, E., Bhatia, S. N., Clish, C. B., and Catteruccia, F., Steroid Hormone Function Controls Non-competitive Plasmodium Development in Anopheles, Cell, vol. 177, no. 2, pp. 315 - 325.e14, 2019.
I. Medina Vera, Ruivo, M. T. Grilo, Rocha, L. F. Lemos, Marques, S., Bhatia, S. N., Mota, M. M., and Mancio-Silva, L., Targeting liver stage malaria with metformin, JCI Insight, vol. 4, no. 24, 2019.
N. Boehnke, Correa, S. , Hao, L. , Wang, W., Straehla, J. P., Bhatia, S. N., and Hammond, P., Theranostic Layer-by-Layer Nanoparticles for Simultaneous Tumor Detection and Gene Silencing, Angewandte Chemie International Edition, 2019.
M. - E. Gilles, Hao, L., Brown, K., Lim, J., Bhatia, S. N., and Slack, F. J., Tumor penetrating nanomedicine targeting both an oncomiR and an oncogene in pancreatic cancer, Oncotarget, vol. 10, no. 51, 2019.
A. Amini, Soleimany, A. , Schwarting, W., Bhatia, S. N., and Rus, D., Uncovering and Mitigating Algorithmic Bias through Learned Latent Structure, AAAI/ACM Conference on Artificial Intelligence, Ethics, and Society, 2019.
N. Gural, Mancio-Silva, L., He, J., and Bhatia, S. N., Engineered Livers for Infectious Diseases, Cellular and Molecular Gastroenterology and Hepatology, vol. 5, no. 2, pp. 131 - 144, 2018.