Found 50 results
Filters: Author is Bhatia, Sangeeta N.  [Clear All Filters]
S. R. Viswanathan, Nogueira, M. F., Buss, C. G., Krill-Burger, J. M., Wawer, M. J., Malolepsza, E., Berger, A. C., Choi, P. S., Shih, J., Taylor, A. M., Tanenbaum, B., Pedamallu, C. Sekhar, Cherniack, A. D., Tamayo, P., Strathdee, C. A., Lage, K., Carr, S. A., Schenone, M., Bhatia, S. N., Vazquez, F., Tsherniak, A., Hahn, W. C., and Meyerson, M., Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer, Nature Genetics, vol. 50, no. 7, pp. 937 - 943, 2018.
J. S. Dudani, Warren, A. D., and Bhatia, S. N., Harnessing Protease Activity to Improve Cancer Care, Annual Review of Cancer Biology, vol. 2, no. 1, 2018.
N. K. Kisalu, Idris, A. H. , Weidle, C., Flores-Garcia, Y., Flynn, B. J., Sack, B. K., Murphy, S., Schön, A., Freire, E., Francica, J. R., Miller, A. B., Gregory, J., March, S., Liao, H. - X., Haynes, B. F., Wiehe, K., Trama, A. M., Saunders, K. O., Gladden, M. A., Monroe, A., Bonsignori, M., Kanekiyo, M., Wheatley, A. K., McDermott, A. B., S Farney, K., Chuang, G. - Y., Zhang, B., Kc, N., Chakravarty, S., Kwong, P. D., Sinnis, P., Bhatia, S. N., Kappe, S. H. I., B Sim, K. Lee, Hoffman, S. L., Zavala, F., Pancera, M. , and Seder, R. A. ‡<, A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite, Nature Medicine, vol. 24, no. 4, pp. 408-416, 2018.
N. Gural, Mancio-Silva, L., Miller, A. B., Galstian, A., Butty, V. L., Levine, S. S., Patrapuvich, R., Desai, S. P., Mikolajczak, S. A., Kappe, S. H. I., Fleming, H. E., March, S., Sattabongkot, J., and Bhatia, S. N., In Vitro Culture, Drug Sensitivity, and Transcriptome of Plasmodium Vivax Hypnozoites, Cell Host & Microbe, vol. 23, no. 3, pp. 395-406, 2018.
J. H. Lo, Hao, L. , Muzumdar, M. D., Raghavan, S., Kwon, E. J., Pulver, E. M., Hsu, F., Aguirre, A. J., Wolpin, B. M., Fuchs, C. S., Hahn, W. C., Jacks, T., and Bhatia, S. N., iRGD-guided tumor-penetrating nanocomplexes for therapeutic siRNA delivery to pancreatic cancer, Molecular Cancer Therapeutics, vol. 17, no. 11, pp. 2377-2388, 2018.
M. - E. Gilles, Hao, L., Huang, L., Rupaimoole, R., Lopez-Casas, P. P., Pulver, E., Jeong, J. Cheol, Muthuswamy, S. K., Hidalgo, M., Bhatia, S. N., and Slack, F. J., Personalized RNA-medicine for pancreatic cancer, Clinical Cancer Research, vol. 24, no. 7, pp. 1734-1747, 2018.
A. M. Mendes, Machado, M., alves-Rosa, Nç, Reuling, I. J., Foquet, L., Marques, áudia, Salman, A. M., Yang, A. S. P., Moser, K. A., Dwivedi, A., Hermsen, C. C., nez-Díaz, éné, Viera, S., Santos, J. M., Albuquerque, ês, Bhatia, S. N., Bial, J., Angulo-Barturen, ñigo, Silva, J. C., Leroux-Roels, G., Janse, C. J., Khan, S. M., Mota, M. M., Sauerwein, R. W., and Prudêncio, M., A Plasmodium berghei sporozoite-based vaccination platform against human malaria, npj Vaccines, vol. 3, 2018.
C. G. Buss, Dudani, J. S. , Akana, R. T. K., Fleming, H. E., and Bhatia, S. N., Protease activity sensors noninvasively classify bacterial infections and antibiotic responses, EBioMedicine, vol. 38, pp. 248-256, 2018.
N. Lippok, Villiger, M., Albanese, A., Meijer, E. F. J., Chung, K., Padera, T. P., Bhatia, S. N., and Bouma, B. E., Depolarization signatures map gold nanorods within biological tissue, Nature Photonics, vol. 11, no. 9, pp. 583-588, 2017.
K. R. Stevens, Scull, M. A., Ramanan, V., Fortin, C. L., Chaturvedi, R. R., Knouse, K. A., Xiao, J. W., Fung, C., Mirabella, T., Chen, A. X., McCue, M. G., Yang, M. T., Fleming, H. E., Chung, K., de Jong, Y. P., Chen, C. S., Rice, C. M., and Bhatia, S. N., In situ expansion of engineered human liver tissue in a mouse model of chronic liver disease, Science Translational Medicine, vol. 9, no. 399, 2017.
E. J. Kwon, Skalak, M., Bertucci, A., Braun, G., Ricci, F., Ruoslahti, E., Sailor, M. J., and Bhatia, S. N., Porous Silicon Nanoparticle Delivery of Tandem Peptide Anti-Infectives for the Treatment of Pseudomonas aeruginosa Lung Infections, Advanced Materials, vol. 29, no. 35, pp. 1-9, 2017.
L. T. Geller, Barzily-Rokni, M. , Danino, T., Jonas, O. H., Shental, N., Nejman, D., Gavert, N., Zwang, Y., Cooper, Z. A., Shee, K., Thaiss, C. A., Reuben, A., Livny, J., Avraham, R., Frederick, D. T., Ligorio, M., Chatman, K., Johnston, S. E., Mosher, C. M., Brandis, A., Fuks, G., Gurbatri, C., Gopalakrishnan, V., Kim, M., Hurd, M. W., Katz, M., Fleming, J., Maitra, A., Smith, D. A., Skalak, M., Bu, J., Michaud, M., Trauger, S. A., Barshack, I., Golan, T., Sandbank, J., Flaherty, K. T., Mandinova, A., Garrett, W. S., Thayer, S. P., Ferrone, C. R., Huttenhower, C., Bhatia, S. N., Gevers, D., Wargo, J. A., Golub, T. R., and Straussman, R., Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine, Science, vol. 35722, no. 6356, pp. 1156 - 1160, 2017.
E. Michailidis, Pabon, J., Xiang, K., Park, P., Ramanan, V., Hoffmann, H. - H., Schneider, W. M., Bhatia, S. N., de Jong, Y. P., Shlomai, A., and Rice, C. M., A robust cell culture system supporting the complete life cycle of hepatitis B virus, Scientific Reports, vol. 7, no. 1, 2017.
S. Ng, March, S., Galstian, A., Gural, N., Stevens, K. R., Mota, M. M., and Bhatia, S. N., Towards a Humanized Mouse Model of Liver Stage Malaria Using Ectopic Artificial Livers, Scientific Reports, vol. 7, no. 45424, 2017.
Y. Ren, Sagers, J. E., Landegger, L. D., Bhatia, S. N., and Stankovic, K. M., Tumor-Penetrating Delivery of siRNA against TNFα to Human Vestibular Schwannomas, Scientific Reports, vol. 7, no. 1, 2017.
E. J. Kwon, Dudani, J. S. , and Bhatia, S. N., Ultrasensitive tumour-penetrating nanosensors of protease activity, Nature Biomedical Engineering, vol. 1, p. 0054, 2017.
J. H. Lo, Kwon, E. J. , Zhang, A. Q., Singhal, P., and Bhatia, S. N., Comparison of Modular PEG Incorporation Strategies for Stabilization of Peptide–siRNA Nanocomplexes, Bioconjugate Chemistry, vol. 27, no. 10, pp. 2323-2331, 2016.
P. K. Jain, Ramanan, V., Schepers, A. G., Dalvie, N. S., Panda, A., Fleming, H. E., and Bhatia, S. N., Development of Light-Activated CRISPR Using Guide RNAs with Photocleavable Protectors, Angewandte Chemie International Edition, vol. 55, no. 40, pp. 12440–12444, 2016.
N. Kato, Comer, E. , Sakata-Kato, T., Sharma, A., Sharma, M., Maetani, M., Bastien, J., Brancucci, N. M., Bittker, J. A., Corey, V., Clarke, D., Derbyshire, E. R., Dornan, G., Duffy, S., Eckley, S., Itoe, M. A., Koolen, K. M. J., Lewis, T. A., Lui, P. S., Lukens, A. K., Lund, E., March, S., Meibalan, E., Meier, B. C., McPhail, J., Mitasev, B., Moss, E. L., Sayes, M., VanGessel, Y., Wawer, M. J., Yoshinaga, T., Zeeman, A. - M., Avery, V. M., Bhatia, S. N., Burke, J. E., Catteruccia, F., Clardy, J. C., Clemons, P. A., Dechering, K. J., Duvall, J. R., Foley, M. A., Gusovsky, F., Kocken, C. H. M., Marti, M., Morningstar, M. L., Munoz, B., Neafsey, D. E., Sharma, A., Winzeler, E. A., Wirth, D. F., Scherer, C. A., and Schreiber, S. L., Diversity-oriented synthesis yields novel multistage antimalarial inhibitors, Nature, vol. 538, no. 7625, pp. 344-349, 2016.
J. Shan, Logan, D. J., Root, D. E., Carpenter, A. E., and Bhatia, S. N., High-Throughput Platform for Identifying Molecular Factors Involved in Phenotypic Stabilization of Primary Human Hepatocytes In Vitro, Journal of Biomolecular Screening, pp. 1-15, 2016.
E. J. Kwon, Skalak, M., Bu, R. Lo, and Bhatia, S. N., Neuron-Targeted Nanoparticle for siRNA Delivery to Traumatic Brain Injuries, ACS Nano, vol. 10, no. 8, pp. 7926–7933, 2016.
J. Joo, Kwon, E. J., Kang, J., Skalak, M., Anglin, E. J., Mann, A. P., Ruoslahti, E., Bhatia, S. N., and Sailor, M. J., Porous silicon–graphene oxide core–shell nanoparticles for targeted delivery of siRNA to the injured brain, Nanoscale Horiz., vol. 1, no. 5, pp. 407 - 414, 2016.
J. Kang, Joo, J., Kwon, E. J., Skalak, M., Hussain, S., She, Z. - G., Ruoslahti, E., Bhatia, S. N., and Sailor, M. J., Self-Sealing Porous Silicon-Calcium Silicate Core-Shell Nanoparticles for Targeted siRNA Delivery to the Injured Brain, Advanced Materials, vol. 28, no. 36, pp. 7962–7969, 2016.
J. S. Dudani, Buss, C. G., Akana, R. T. K., Kwong, G. A., and Bhatia, S. N., Sustained-Release Synthetic Biomarkers for Monitoring Thrombosis and Inflammation Using Point-of-Care Compatible Readouts, Advanced Functional Materials, vol. 26, no. 17, pp. 2919-2928, 2016.
V. A. Liu and Bhatia, S. N., Three-Dimensional Photopatterning of Hydrogels Containing Living Cells, Biomedical Microdevices, vol. 4, no. 4, pp. 257 - 266, 2002.