Found 232 results
M. A. Phillips, Lotharius, J., Marsh, K., White, J., Dayan, A., White, K. L., Njoroge, J. W., Mazouni, F. El, Lao, Y., Kokkonda, S., Tomchick, D. R., Deng, X., Laird, T., Bhatia, S. N., March, S., Ng, C. L., Fidock, D. A., Wittlin, S., Lafuente-Monasterio, M., Benito, F. Javier Gam, Alonso, L. Maria Sanz, Martinez, M. Santos, Jimenez-Diaz, M. Belen, Bazaga, S. Ferrer, Angulo-Barturen, I., Haselden, J. N., Louttit, J., Cui, Y., Sridhar, A., Zeeman, A. - M., Kocken, C., Sauerwein, R., Dechering, K., Avery, V. M., Duffy, S., Delves, M., Sinden, R., Ruecker, A., Wickham, K. S., Rochford, R., Gahagen, J., Iyer, L., Riccio, E., Mirsalis, J., Bathhurst, I., Rueckle, T., Ding, X., Campo, B., Leroy, D., M. Rogers, J., Rathod, P. K., Burrows, J. N., and Charman, S. A. , A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria, Science Translational Medicine, vol. 7, pp. 296ra111–296ra111, 2015.
G. A. Kwong, Dudani, J. S., Carrodeguas, E., Mazumdar, E. V., Zekavat, S. M., and Bhatia, S. N., Mathematical framework for activity-based cancer biomarkers, Proceedings of the National Academy of Sciences, 2015.
S. March, Ramanan, V., Trehan, K., Ng, S., Galstian, A., Gural, N., Scull, M. A., Shlomai, A., Mota, M. M., Fleming, H. E., Khetani, S. R., Rice, C. M., and Bhatia, S. N., Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens, Nat. Protocols, vol. 10, no. 12, pp. 2027 - 2053, 2015.
R. R. Chaturvedi, Stevens, K. R., Solorzano, R. D., Schwartz, R. E., Eyckmans, J., Baranski, J. D., Stapleton, S. Chase, Bhatia, S. N., and Chen, C. S., Patterning vascular networks in vivo for tissue engineering applications., Tissue Eng Part C Methods, vol. 21, no. 5, pp. 509-17, 2015.
J. S. Dudani, Jain, P. K., Kwong, G. A., Stevens, K. R., and Bhatia, S. N., Photoactivated Spatiotemporally-Responsive Nanosensors of in Vivo Protease Activity., ACS Nano, vol. 9, no. 12, pp. 11708-17, 2015.
T. Danino, Prindle, A. , Kwong, G. A., Skalak, M., Li, H., Allen, K., Hasty, J. , and Bhatia, S. N., Programmable probiotics for detection of cancer in urine, Science Translational Medicine, vol. 7, p. 289ra84–, 2015.
E. J. Kwon, Lo, J. H., and Bhatia, S. N., Smart nanosystems: Bio-inspired technologies that interact with the host environment., Proc Natl Acad Sci U S A, vol. 112, no. 47, pp. 14460-6, 2015.
S. N. Bhatia, Underhill, G. H., Zaret, K. S., and Fox, I. J., Cell and tissue engineering for liver disease., Sci Transl Med, vol. 6, no. 245, p. 245sr2, 2014.
D. Ghosh, Bagley, A. F., Na, Y. Jeong, Birrer, M. J., Bhatia, S. N., and Belcher, A. M., Deep, noninvasive imaging and surgical guidance of submillimeter tumors using targeted M13-stabilized single-walled carbon nanotubes., Proc Natl Acad Sci U S A, vol. 111, no. 38, pp. 13948-53, 2014.
A. D. Warren, Gaylord, S. T., Ngan, K. C., Milutinovic, M. Dumont, Kwong, G. A., Bhatia, S. N., and Walt, D. R., Disease detection by ultrasensitive quantification of microdosed synthetic urinary biomarkers., J Am Chem Soc, vol. 136, no. 39, pp. 13709-14, 2014.
K. Y. Lin, Kwon, E. J., Lo, J., and Bhatia, S. N., Drug-induced amplification of nanoparticle targeting to tumors, Nano Today, vol. 9, pp. 550 - 559, 2014.
M. A. Itoe, Sampaio, J. L., Cabal, G. G., Real, E., Zuzarte-Luis, V., March, S., Bhatia, S. N., Frischknecht, F., Thiele, C., Shevchenko, A., and Mota, M. M., Host cell phosphatidylcholine is a key mediator of malaria parasite survival during liver stage infection., Cell Host Microbe, vol. 16, no. 6, pp. 778-86, 2014.
S. Ng, March, S., Galstian, A., Hanson, K., Carvalho, T., Mota, M. M., and Bhatia, S. N., Hypoxia promotes liver-stage malaria infection in primary human hepatocytes in vitro., Dis Model Mech, vol. 7, no. 2, pp. 215-24, 2014.
E. E. Hui, Li, C., Agrawal, A., and Bhatia, S. N., Macro-to-Micro Interface for the Control of Cellular Organization, Journal of Microelectromechanical Systems, vol. 23, pp. 391–397, 2014.
S. Hauert and Bhatia, S. N., Mechanisms of cooperation in cancer nanomedicine: towards systems nanotechnology., Trends Biotechnol, vol. 32, no. 9, pp. 448-55, 2014.
S. N. Bhatia and Ingber, D. E., Microfluidic organs-on-chips., Nat Biotechnol, vol. 32, no. 8, pp. 760-72, 2014.
C. Y. Li, Stevens, K. R., Schwartz, R. E., Alejandro, B. S., Huang, J. H., and Bhatia, S. N., Micropatterned cell-cell interactions enable functional encapsulation of primary hepatocytes in hydrogel microtissues., Tissue Eng Part A, vol. 20, no. 15-16, pp. 2200-12, 2014.
A. Shlomai, Schwartz, R. E., Ramanan, V., Bhatta, A., de Jong, Y. P., Bhatia, S. N., and Rice, C. M., Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems., Proc Natl Acad Sci U S A, vol. 111, no. 33, pp. 12193-8, 2014.
V. Ramanan, Scull, M. A. , Sheahan, T. P., Rice, C. M., and Bhatia, S. N., New Methods in Tissue Engineering: Improved Models for Viral Infection, Annual Review of Virology, vol. 1, pp. 475-499, 2014.
R. E. Schwartz, Fleming, H. E., Khetani, S. R., and Bhatia, S. N., Pluripotent stem cell-derived hepatocyte-like cells., Biotechnol Adv, vol. 32, no. 2, pp. 504-13, 2014.
A. D. Warren, Kwong, G. A. , Wood, D. K. , Lin, K. Y., and Bhatia, S. N., Point-of-care diagnostics for noncommunicable diseases using synthetic urinary biomarkers and paper microfluidics., Proc Natl Acad Sci U S A, vol. 111, no. 10, pp. 3671-6, 2014.
K. Y. Lin, Lo, J. H., Consul, N., Kwong, G. A., and Bhatia, S. N., Self-titrating anticoagulant nanocomplexes that restore homeostatic regulation of the coagulation cascade., ACS Nano, vol. 8, no. 9, pp. 8776-85, 2014.
S. Olcum, Cermak, N. , Wasserman, S. C., Christine, K. S., Atsumi, H., Payer, K. R., Shen, W., Lee, J., Belcher, A. M., Bhatia, S. N., and Manalis, S. R., Weighing nanoparticles in solution at the attogram scale., Proc Natl Acad Sci U S A, vol. 111, no. 4, pp. 1310-5, 2014.