Publications
Microscale culture of human liver cells for drug development
S. Khetani and S. Bhatia.
Nature Biotechnology (2008)
Manuscript (PDF), Supporting information (PDF)
Identification of small molecules for human hepatocyte expansion and iPS differentiation
J. Shan, R.E. Schwartz, N.T. Ross, D.J. Logan, D. Thomas, S.A Duncan, T.E. North, W. Goessling, A.E. Carpenter, and S.N. Bhatia
Nature Chemical Biology (2013)
Manuscript (PDF), Supporting information (PDF)
In situ expansion of engineered human liver tissue in a mouse model of chronic liver disease
K. R. Stevens, M.A. Scull, V. Ramanan, C.L. Fortin, R.R. Chaturvedi, K.A. Knouse, J.W. Xiao, C. Fung, T. Mirabella, A.X. Chen, M.G. McCue, M.T. Yang, H.E. Fleming, K. Chung, Y.P. de Jong, C.S. Chen, C.M. Rice, and S.N. Bhatia.
Science Translational Medicine (2017)
Manuscript (PDF), Supporting information (PDF)
Improving drug discovery by nucleic acid delivery in engineered human microlivers
L. Mancio-Silva, H. E. Fleming, A. B. Miller, S. Milstein, A. Liebow, P. Haslett, L. Sepp-Lorenzino, and S. N. Bhatia.
Cell Metabolism (2019)
Manuscript (PDF), Supporting information (PDF)