Publications
Engineering multiplexed synthetic breath biomarkers as diagnostic probes.
Wang, S-T., Anahtar, M., Kim, D.M., Samad, T.S., Zheng, C.M., Patel, S., Ko, H., Ngambenjawong, C., Wang, C.S., Kirkpatrick, J.D., Kumar, V., Fleming, H.E., and Bhatia, S.N.
bioRxiv (2024)
Manuscript (PDF)
Conditional fusogenic lipid nanocarriers for cytosolic delivery of macromolecular therapeutics
Zhong, Q., Tan, E.K., Shyamal, A., Ngambenjawong, C., Parisi, T., Ko, H., Fleming, H.E., Jacks, T., and Bhatia, S.N.
bioRxiv (2024)
Manuscript (PDF)
Mapping Plasmodium transitions and interactions in the Anopheles female
Yan, Y., Cheung, E., Verzier, L.H., Appetecchia, F., March, S., Craven, A.R., Du, E., Probst, A.S., Rinvee, T.A., de Vries, L.E., Kauffman, J., Bhatia, S.N., Nelson, E., Singh, N., Peng, D., Shaw, W.R., and Catteruccia, F.
bioRxiv (2024)
Manuscript (PDF)
Expandable, functional hepatocytes derived from primary cells enable liver therapeutics
Mallanna, S.K., Karanth, S.S., Marturano, J.E., Kudva, A.K., Lehmann, M., Morse, J.K., Jamiel, M., Norman, T., Wilson, C., Munarin, F., Broderick, D., Van Buskirk, M., Uddin, E., Ret, M., Steele, C., Cheema, M., Black, J., Vanderploeg, E., Chen, C., Bhatia, S.N., Rezania, A., Lowery, T.J., Cazanave, S., and Chhabra, A.
bioRxiv (2024)
Manuscript (PDF)
Modulating cell-free DNA biology as the next frontier in liquid biopsies
Tabrizi, S., Martin-Alonso, C., Xiong, K., Bhatia, S.N.*, Adalsteinsson, V.A.*, and Love, C.J.*
Trends in Cell Biology (2024)
Manuscript (PDF)
Nanobody-targeted conditional antimicrobial therapeutics
Ngambenjawong, C., Ko, H., Pishesha, N., Ploegh, H. L., and Bhatia, S.N.
BioRxiv (2024)
Manuscript (PDF)
CRISPR-Cas-mediated Multianalyte Synthetic Urine Biomarker Test for Portable Diagnostics
Van Heest AE, Deng F, Zhao RT, Harzallah NS, Fleming HE, Bhatia SN, Hao L.
JoVE (2023)
Manuscript (PDF)
Enhancing the immunogenicity of lipid-nanoparticle mRNA vaccines by adjuvanting the ionizable lipid and the mRNA
Li B, Jiang AY, Raji I, Atyeo C, Raimondo TM, Gordon AGR, Rhym LH, Samad T, MacIsaac C, Witten J, Mughal H, Chicz TM, Xu Y, McNamara RP, Bhatia S, Alter G, Langer R, Anderson DG.
Nature Biomedical Engineering (2023)
Manuscript (PDF)
Autonomous circadian rhythms in the human hepatocyte regulate hepatic drug metabolism and inflammatory responses
Targeting and monitoring ovarian cancer invasion with an RNAi and peptide delivery system
Liangliang Hao, Natalie Boehnke, Susanna K. Elledge, Nour-Saïda Harzallah, Renee T. Zhao, Eva Cai, Yu-XiongFeng, Sofia Neaher, Heather E. Fleming, Piyush B. Gupta, Paula T. Hammond, and Sangeeta N. Bhatia.
PNAS (2024)
Manuscript: (PDF)
Priming agents transiently reduce the clearance of cell-free DNA to improve liquid biopsies
Carmen Martin-Alonso, Shervin Tabrizi , Kan Xiong, Timothy Blewett, Sainetra Sridhar, Andjela Crnjac, Sahil Patel, Zhenyi An, Ahmet Bekdemir, Douglas Shea, Shih-Ting Wang, Sergio Rodriguez-Aponte, Christopher A. Naranjo, Justin Rhoades, Jesse D. Kirkpatrick, Heather E. Fleming, Ava P. Amini, Todd R. Golub, J. Christopher Love , Sangeeta N. Bhatia, and Viktor A. Adalsteinsson.
Science (2024)
Manuscript (PDF)
Cited by:
Tina Moser, Ellen Heitzer, Surpassing sensitivity limits in liquid biopsy. Science383,260-261 (2024). (PDF).
Sarah Crunkhorn, Improving liquid biopsy for cancer detection. Nature Reviews Drug Discovery (2024). (PDF).
News coverage:
CRISPR-Cas-amplified urinary biomarkers for multiplexed and portable cancer diagnostics
Liangliang Hao, Renee T. Zhao, Nicole L. Welch, Edward Kah Wei Tan, Qian Zhong, Nour Saida Harzallah, Chayanon Ngambenjawong, Henry Ko, Heather E. Fleming, Pardis C. Sabeti & Sangeeta N. Bhatia
Nature Nanotechnology (2023)
Manuscript (PDF)
Low protease activity in B cell follicles promotes retention of intact antigens after immunization
Aereas Aung, Ang Cui, Laura Maiorino, Ava P. Amini, Justin R. Gregory, Maurice Bukenya, Yiming Zhang, Heya Lee, Christopher A. Cottrell, Duncan M. Morgan, Murillo Silva, Heikyung Suh, Jesse D. Kirkpatrick, Parastoo Amlashi, Tanaka Remba, Leah M. Froehle, Shuhao Xiao, Wuhbet Abraham, Josetta Adams, J. Christopher Love, Phillip Huyett, Douglas S. Kwon, Nir Hacohen, William R. Schief, Sangeeta N. Bhatia, Darrell J. Irvine
Science (2023)
Manuscript (PDF)
Cancer nanomedicine
Sangeeta N. Bhatia , Xiaoyuan Chen , Marina A. Dobrovolskaia and Twan Lammers
Nature Cancer Reviews (2022)
Manuscript (PDF)
Ebola virus infection induces a delayed type I IFN response in bystander cells and the shutdown of key liver genes in human iPSC-derived hepatocytes
Whitney A. Scoon, Liliana Mancio-Silva, Ellen L. Suder, Carlos Villacorta-Martin, Jonathan Lindstrom-Vautrin, John G. Bernbaum, Steve Mazur, Reed F. Johnson, Judith Olejnik, Elizabeth Y. Flores, Aditya Mithal, Feiya Wang, Adam J. Hume, Joseph E. Kaserman, Sandra March-Riera, Andrew A. Wilson, Sangeeta N. Bhatia, Elke Mühlberger, Gustavo Mostoslavsky
Cell Reports (2022)
