Publications
Protease activity sensors noninvasively classify bacterial infections and antibiotic responses
C. Buss †, J.S. Dudani †, R. Akana, H.E. Fleming, and S.N. Bhatia
EBioMedicine (2018)
Manuscript (PDF), Supporting information (PDF)
Harnessing Protease Activity to Improve Cancer Care
J.S. Dudani, A.D. Warren, S.N. Bhatia.
Annu. Rev. Cancer Biol. 2, (2018).
A Plasmodium berghei sporozoite-based vaccination platform against human malaria
A. M. Mendes, Machado, M., alves-Rosa, Nç, Reuling, I. J., Foquet, L., Marques, áudia, Salman, A. M., Yang, A. S. P., Moser, K. A., Dwivedi, A., Hermsen, C. C., nez-Díaz, éné, Viera, S., Santos, J. M., Albuquerque, ês, Bhatia, S. N., Bial, J., Angulo-Barturen, ñigo, Silva, J. C., Leroux-Roels, G., Janse, C. J., Khan, S. M., Mota, M. M., Sauerwein, R. W., and Prudêncio, M.
npj Vaccines, vol. 3, 2018.
Manuscript (PDF), Supporting information (PDF)
iRGD-guided tumor-penetrating nanocomplexes for therapeutic siRNA delivery to pancreatic cancer
J. H. Lo†, Hao, L. †, Muzumdar, M. D., Raghavan, S., Kwon, E. J., Pulver, E. M., Hsu, F., Aguirre, A. J., Wolpin, B. M., Fuchs, C. S., Hahn, W. C., Jacks, T., and Bhatia, S. N.
Molecular Cancer Therapeutics, vol. 17, no. 11, pp. 2377-2388, 2018.
Manuscript (PDF), Supporting information (PDF)
Classification of prostate cancer using a protease activity nanosensor library
J. S. Dudani, Ibrahim, M., Kirkpatrick, J., Warren, A. D., and Bhatia, S. N.
Proc Natl Acad Sci U S A, vol. 115, no. 36, pp. 8954-8959, 2018.
Manuscript (PDF), Supporting information (PDF)
Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer
S. R. Viswanathan, Nogueira, M. F., Buss, C. G., Krill-Burger, J. M., Wawer, M. J., Malolepsza, E., Berger, A. C., Choi, P. S., Shih, J., Taylor, A. M., Tanenbaum, B., Pedamallu, C. Sekhar, Cherniack, A. D., Tamayo, P., Strathdee, C. A., Lage, K., Carr, S. A., Schenone, M., Bhatia, S. N., Vazquez, F., Tsherniak, A., Hahn, W. C., and Meyerson, M.
Nature Genetics, vol. 50, no. 7, pp. 937 - 943, 2018.
Manuscript (PDF), Supporting information (PDF)
A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite
Kisalu, N.K., Idris, A.H., Weidle, C., Flores-Garcia, Y., Flynn, B.J., Sack, B.K., Murphy, Schön A., Freire, E., Francica, J.R., Miller, A.B., Gregory, J., March, S., Liao, H.X., Haynes, B.F., Wiehe, K., Trama, A.M., Saunders, K.O., Gladden, M.A., Monroe, A., Bonsignori, M., Kanekiyo, M., Wheatley, A.K., McDermott, A.B., Farney, S.K., Chuang, G.Y., Zhang, B., Kc, N., Chakravarty, S., Kwong, P.D., Sinnis, P., Bhatia, S.N., Kappe, S.H.I., Sim, B.K.L., Hoffman, S.L., Zavala, F., Pancera, M., and Seder, R.A.
Nature Medicine (2018)
Manuscript (PDF), Supporting information (PDF)
In vitro culture, drug sensitivity, and transcriptome of plasmodium vivax hypnozoites
N. Gural, L. Mancio-Silva, A.B. Miller, A. Galstian, V.L. Butty, S.S. Levine, R. Patrapuvich, S.P. Desai, S.A. Mikolajczak, S.H.I. Kappe, H.E. Fleming, S. March, J. Sattabongkot, and S.N. Bhatia
Cell Host & Microbe (2018)
Manuscript (PDF), Supporting information (PDF)
Personalized RNA-medicine for pancreatic cancer
M. - E. Gilles, Hao, L., Huang, L., Rupaimoole, R., Lopez-Casas, P. P., Pulver, E., Jeong, J. Cheol, Muthuswamy, S. K., Hidalgo, M., Bhatia, S. N., and Slack, F. J.
Clinical Cancer Research, vol. 24, no. 7, pp. 1734-1747, 2018.
Manuscript (PDF)
Engineered Livers for Infectious Diseases
N. Gural, Mancio-Silva, L., He, J., and Bhatia, S. N.
Cellular and Molecular Gastroenterology and Hepatology (2018)
Manuscript (PDF)