LMRT 12/22/18 LMRT 12/22/18

Protease activity sensors noninvasively classify bacterial infections and antibiotic responses

C. Buss †, J.S. Dudani †, R. Akana, H.E. Fleming, and S.N. Bhatia
EBioMedicine (2018)

Manuscript (PDF), Supporting information (PDF)

LMRT 9/23/18 LMRT 9/23/18

Harnessing Protease Activity to Improve Cancer Care

J.S. Dudani, A.D. Warren, S.N. Bhatia.
Annu. Rev. Cancer Biol. 2, (2018).

Manuscript (PDF)

Melodi Anahtar 8/24/18 Melodi Anahtar 8/24/18

A Plasmodium berghei sporozoite-based vaccination platform against human malaria

A. M. Mendes, Machado, M., alves-Rosa, Nç, Reuling, I. J., Foquet, L., Marques, áudia, Salman, A. M., Yang, A. S. P., Moser, K. A., Dwivedi, A., Hermsen, C. C., nez-Díaz, éné, Viera, S., Santos, J. M., Albuquerque, ês, Bhatia, S. N., Bial, J., Angulo-Barturen, ñigo, Silva, J. C., Leroux-Roels, G., Janse, C. J., Khan, S. M., Mota, M. M., Sauerwein, R. W., and Prudêncio, M.
npj Vaccines, vol. 3, 2018.

Manuscript (PDF), Supporting information (PDF)

Melodi Anahtar 8/10/18 Melodi Anahtar 8/10/18

iRGD-guided tumor-penetrating nanocomplexes for therapeutic siRNA delivery to pancreatic cancer

J. H. Lo†, Hao, L. †, Muzumdar, M. D., Raghavan, S., Kwon, E. J., Pulver, E. M., Hsu, F., Aguirre, A. J., Wolpin, B. M., Fuchs, C. S., Hahn, W. C., Jacks, T., and Bhatia, S. N.
Molecular Cancer Therapeutics, vol. 17, no. 11, pp. 2377-2388, 2018.

Manuscript (PDF), Supporting information (PDF)

Melodi Anahtar 8/1/18 Melodi Anahtar 8/1/18

Classification of prostate cancer using a protease activity nanosensor library

J. S. Dudani, Ibrahim, M., Kirkpatrick, J., Warren, A. D., and Bhatia, S. N.
Proc Natl Acad Sci U S A, vol. 115, no. 36, pp. 8954-8959, 2018.

Manuscript (PDF), Supporting information (PDF)

Melodi Anahtar 7/1/18 Melodi Anahtar 7/1/18

Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer

S. R. Viswanathan, Nogueira, M. F., Buss, C. G., Krill-Burger, J. M., Wawer, M. J., Malolepsza, E., Berger, A. C., Choi, P. S., Shih, J., Taylor, A. M., Tanenbaum, B., Pedamallu, C. Sekhar, Cherniack, A. D., Tamayo, P., Strathdee, C. A., Lage, K., Carr, S. A., Schenone, M., Bhatia, S. N., Vazquez, F., Tsherniak, A., Hahn, W. C., and Meyerson, M.
Nature Genetics, vol. 50, no. 7, pp. 937 - 943, 2018.

Manuscript (PDF), Supporting information (PDF)

Melodi Anahtar 3/29/18 Melodi Anahtar 3/29/18

A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite

Kisalu, N.K., Idris, A.H., Weidle, C., Flores-Garcia, Y., Flynn, B.J., Sack, B.K., Murphy, Schön A., Freire, E., Francica, J.R., Miller, A.B., Gregory, J., March, S., Liao, H.X., Haynes, B.F., Wiehe, K., Trama, A.M., Saunders, K.O., Gladden, M.A., Monroe, A., Bonsignori, M., Kanekiyo, M., Wheatley, A.K., McDermott, A.B., Farney, S.K., Chuang, G.Y., Zhang, B., Kc, N., Chakravarty, S., Kwong, P.D., Sinnis, P., Bhatia, S.N., Kappe, S.H.I., Sim, B.K.L., Hoffman, S.L., Zavala, F., Pancera, M., and Seder, R.A.
Nature Medicine (2018)

Manuscript (PDF), Supporting information (PDF)

Melodi Anahtar 3/14/18 Melodi Anahtar 3/14/18

In vitro culture, drug sensitivity, and transcriptome of plasmodium vivax hypnozoites

N. Gural, L. Mancio-Silva, A.B. Miller, A. Galstian, V.L. Butty, S.S. Levine, R. Patrapuvich, S.P. Desai, S.A. Mikolajczak, S.H.I. Kappe, H.E. Fleming, S. March, J. Sattabongkot, and S.N. Bhatia
Cell Host & Microbe (2018)

Manuscript (PDF), Supporting information (PDF)

Melodi Anahtar 1/12/18 Melodi Anahtar 1/12/18

Personalized RNA-medicine for pancreatic cancer

M. - E. Gilles, Hao, L., Huang, L., Rupaimoole, R., Lopez-Casas, P. P., Pulver, E., Jeong, J. Cheol, Muthuswamy, S. K., Hidalgo, M., Bhatia, S. N., and Slack, F. J.
Clinical Cancer Research, vol. 24, no. 7, pp. 1734-1747, 2018.

Manuscript (PDF)