Publications
2021
“Virtual Undergraduate Research Experiences: More Than a Pandemic Stopgap”, Med, no. 2, pp. 118 - 121, 2021. ,
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“Fusogenic Porous Silicon Nanoparticles as a Broad-Spectrum Immunotherapy Against Bacterial Infections”, Nanoscale Horizons, 2021. ,
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2020
“Activatable zymography probes enable in situ localization of protease dysregulation in cancer”, Cancer Research, vol. 81, no. 1, pp. 213-224, 2020. ,
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Supporting information


“Mapping functional humoral correlates of protection against malaria challenge following RTS,S/AS01 vaccination”, Science Translational Medicine, vol. 12, no. 553, p. eabb4757, 2020. ,
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Supporting material


“Peptide Spiders: Peptide–Polymer Conjugates to Traffic Nucleic AcidsPeptide Spiders: PeptidePolymer Conjugates to Traffic Nucleic Acids”, Molecular Pharmaceutics, 2020. ,
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Supporting information


“Engineering synthetic breath biomarkers for respiratory disease”, Nature Nanotechnology, 2020. ,
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“CRISPR-Cas-amplified urine biomarkers for multiplexed and portable cancer diagnostics”, bioRxiv, 2020. ,
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“Controlled Apoptosis of Stromal Cells to Engineer Human Microlivers”, Advanced Functional Materials, vol. 60, 2020. ,
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“Nanoparticle delivery of immunostimulatory oligonucleotides enhances response to checkpoint inhibitor therapeutics”, Proceedings of the National Academy of Sciences, 2020. ,
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“Pharmacokinetic tuning of protein–antigen fusions enhances the immunogenicity of T-cell vaccines”, Nature Biomedical Engineering, 2020. ,
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“Cancer Cell–Derived Matrisome Proteins Promote Metastasis in Pancreatic Ductal Adenocarcinoma”, Cancer Research, vol. 80, no. 7, pp. 1461 - 1474, 2020. ,
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“Expansion, in vivo–ex vivo cycling, and genetic manipulation of primary human hepatocytes”, Proceedings of the National Academy of Sciences, vol. 117, no. 3, pp. 1678 - 1688, 2020. ,
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“Activity-Based Diagnostics: An Emerging Paradigm for Disease Detection and Monitoring”, Trends in Molecular Medicine, 2020. ,
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“Urinary detection of lung cancer in mice via noninvasive pulmonary protease profiling”, Science Translational Medicine, vol. 12, no. 537, p. eaaw0262, 2020. ,
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Supporting information


“Genetic Encoding of Targeted Magnetic Resonance Imaging Contrast Agents for Tumor Imaging”, ACS Synthetic Biology, 2020. ,
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Supporting information


“QnAs with Sangeeta N. Bhatia”, Proceedings of the National Academy of Sciences, p. 201922176, 2020. ,
1922176117.full_.pdf

2019
“Antimalarial activity of primaquine operates via a two-step biochemical relay”, Nature Communications, vol. 10, no. 3226, 2019. ,
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“Targeting liver stage malaria with metformin”, JCI Insight, vol. 4, no. 24, 2019. ,
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“Theranostic Layer-by-Layer Nanoparticles for Simultaneous Tumor Detection and Gene Silencing”, Angewandte Chemie International Edition, 2019. ,
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Supporting information


“Non-viral delivery of CRISPR/Cas9 complex using CRISPR-GPS nanocomplexes”, Nanoscale, vol. 11, no. 441, pp. 21317 - 21323, 2019. ,
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Supporting information


“Tumor penetrating nanomedicine targeting both an oncomiR and an oncogene in pancreatic cancer”, Oncotarget, vol. 10, no. 51, 2019. ,
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“Renal clearable catalytic gold nanoclusters for in vivo disease monitoring”, Nature Nanotechnology, 2019. ,
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“Synthetic and living micropropellers for convection-enhanced nanoparticle transport”, Science Advances, vol. 5, no. 4, p. eaav4803, 2019. ,
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Supporting Information


“Steroid Hormone Function Controls Non-competitive Plasmodium Development in Anopheles”, Cell, vol. 177, no. 2, pp. 315 - 325.e14, 2019. ,
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Supporting Information


“Acidification of tumor at stromal boundaries drives transcriptome alterations associated with aggressive phenotypes”, Cancer Research, 2019. ,
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“Improving Drug Discovery by Nucleic Acid Delivery in Engineered Human Microlivers”, Cell Metabolism, vol. 29, no. 3, pp. 727 - 735.e3, 2019. ,
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Supporting Information


“Uncovering and Mitigating Algorithmic Bias through Learned Latent Structure”, AAAI/ACM Conference on Artificial Intelligence, Ethics, and Society, 2019. ,
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“Estrogen Activation of G protein-coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes”, Gastroenterology, 2019. ,
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2018
“Protease activity sensors noninvasively classify bacterial infections and antibiotic responses”, EBioMedicine, vol. 38, pp. 248-256, 2018. ,
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Supporting information


“A Plasmodium berghei sporozoite-based vaccination platform against human malaria”, npj Vaccines, vol. 3, 2018. ,
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“Classification of prostate cancer using a protease activity nanosensor library.”, Proc Natl Acad Sci U S A, vol. 115, no. 36, pp. 8954-8959, 2018. ,
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“iRGD-guided tumor-penetrating nanocomplexes for therapeutic siRNA delivery to pancreatic cancer”, Molecular Cancer Therapeutics, vol. 17, no. 11, pp. 2377-2388, 2018. ,
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“Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer”, Nature Genetics, vol. 50, no. 7, pp. 937 - 943, 2018. ,
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“A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite”, Nature Medicine, vol. 24, no. 4, pp. 408-416, 2018. ,
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“In Vitro Culture, Drug Sensitivity, and Transcriptome of Plasmodium Vivax Hypnozoites”, Cell Host & Microbe, vol. 23, no. 3, pp. 395-406, 2018. ,
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“Personalized RNA-medicine for pancreatic cancer”, Clinical Cancer Research, vol. 24, no. 7, pp. 1734-1747, 2018. ,
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“Engineered Livers for Infectious Diseases”, Cellular and Molecular Gastroenterology and Hepatology, vol. 5, no. 2, pp. 131 - 144, 2018. ,
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“Harnessing Protease Activity to Improve Cancer Care”, Annual Review of Cancer Biology, vol. 2, no. 1, 2018. ,
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2017
“Tumor-Penetrating Delivery of siRNA against TNFα to Human Vestibular Schwannomas”, Scientific Reports, vol. 7, no. 1, 2017. ,
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“A robust cell culture system supporting the complete life cycle of hepatitis B virus”, Scientific Reports, vol. 7, no. 1, 2017. ,
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“Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine”, Science, vol. 35722, no. 6356, pp. 1156 - 1160, 2017. ,
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“Future cancer research priorities in the USA: a Lancet Oncology Commission”, The Lancet Oncology, vol. 18, no. 11, pp. e653 - e706, 2017. ,
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“Depolarization signatures map gold nanorods within biological tissue”, Nature Photonics, vol. 11, no. 9, pp. 583-588, 2017. ,
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“In situ expansion of engineered human liver tissue in a mouse model of chronic liver disease”, Science Translational Medicine, vol. 9, no. 399, 2017. ,
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“Porous Silicon Nanoparticle Delivery of Tandem Peptide Anti-Infectives for the Treatment of Pseudomonas aeruginosa Lung Infections”, Advanced Materials, vol. 29, no. 35, pp. 1-9, 2017. ,
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“Ultrasensitive tumour-penetrating nanosensors of protease activity”, Nature Biomedical Engineering, vol. 1, p. 0054, 2017. ,
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“Towards a Humanized Mouse Model of Liver Stage Malaria Using Ectopic Artificial Livers”, Scientific Reports, vol. 7, no. 45424, 2017. ,
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Supporting Information


2016
“Magnetically Actuated Protease Sensors for in Vivo Tumor Profiling”, Nano Letters, vol. 16, no. 10, pp. 6303–6310, 2016. ,
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“Comparison of Modular PEG Incorporation Strategies for Stabilization of Peptide–siRNA Nanocomplexes”, Bioconjugate Chemistry, vol. 27, no. 10, pp. 2323-2331, 2016. ,
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“Diversity-oriented synthesis yields novel multistage antimalarial inhibitors”, Nature, vol. 538, no. 7625, pp. 344-349, 2016. ,
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“Host AMPK Is a Modulator of Plasmodium Liver Infection.”, Cell Rep, vol. 16, no. 10, pp. 2539-45, 2016. ,
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“Infection of laboratory colonies of Anopheles mosquitoes with Plasmodium vivax from cryopreserved clinical isolates.”, Int J Parasitol, vol. 46, no. 11, pp. 679-683, 2016. ,
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“Development of Light-Activated CRISPR Using Guide RNAs with Photocleavable Protectors”, Angewandte Chemie International Edition, vol. 55, no. 40, pp. 12440–12444, 2016. ,
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“Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond”, PLOS Pathogens, vol. 12, no. 7, 2016. ,
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“Neuron-Targeted Nanoparticle for siRNA Delivery to Traumatic Brain Injuries”, ACS Nano, vol. 10, no. 8, pp. 7926–7933, 2016. ,
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“Synchronized cycles of bacterial lysis for in vivo delivery”, Nature, vol. 536, no. 7614, pp. 81-85, 2016. ,
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“A peptide for targeted, systemic delivery of imaging and therapeutic compounds into acute brain injuries.”, Nat Commun, vol. 7, p. 11980, 2016. ,
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“Self-Sealing Porous Silicon-Calcium Silicate Core-Shell Nanoparticles for Targeted siRNA Delivery to the Injured Brain”, Advanced Materials, vol. 28, no. 36, pp. 7962–7969, 2016. ,
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“Engineering a perfusable 3D human liver platform from iPS cells”, Lab Chip, vol. 16, pp. 2644-2653, 2016. ,
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“Porous silicon–graphene oxide core–shell nanoparticles for targeted delivery of siRNA to the injured brain”, Nanoscale Horiz., vol. 1, no. 5, pp. 407 - 414, 2016. ,
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“High-Throughput Platform for Identifying Molecular Factors Involved in Phenotypic Stabilization of Primary Human Hepatocytes In Vitro”, Journal of Biomolecular Screening, pp. 1-15, 2016. ,
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“Viral genome imaging of hepatitis C virus to probe heterogeneous viral infection and responses to antiviral therapies”, Virology, vol. 494, pp. 236 - 247, 2016. ,
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“Sustained-Release Synthetic Biomarkers for Monitoring Thrombosis and Inflammation Using Point-of-Care Compatible Readouts”, Advanced Functional Materials, vol. 26, no. 17, pp. 2919-2928, 2016. ,
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“Voices of biotech”, Nature Biotechnology, vol. 34, no. 3, pp. 270 - 275, 2016. ,
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“Quantifying co-cultured cell phenotypes in high-throughput using pixel-based classification.”, Methods, vol. 96, pp. 6-11, 2016. ,
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“Extracellular matrix microarrays to study inductive signaling for endoderm specification.”, Acta Biomater, vol. 34, pp. 30-40, 2016. ,
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2015
“Photoactivated Spatiotemporally-Responsive Nanosensors of in Vivo Protease Activity.”, ACS Nano, vol. 9, no. 12, pp. 11708-17, 2015. ,
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“Smart nanosystems: Bio-inspired technologies that interact with the host environment.”, Proc Natl Acad Sci U S A, vol. 112, no. 47, pp. 14460-6, 2015. ,
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“Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens”, Nat. Protocols, vol. 10, no. 12, pp. 2027 - 2053, 2015. ,
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“Mathematical framework for activity-based cancer biomarkers”, Proceedings of the National Academy of Sciences, 2015. ,
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“Endothelial Thermotolerance Impairs Nanoparticle Transport in Tumors.”, Cancer Res, vol. 75, no. 16, pp. 3255-67, 2015. ,
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“A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria”, Science Translational Medicine, vol. 7, pp. 296ra111–296ra111, 2015. ,
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“CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus”, Sci. Rep., vol. 5, 2015. ,
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“Programmable probiotics for detection of cancer in urine”, Science Translational Medicine, vol. 7, p. 289ra84–, 2015. ,
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Recommended by Faculty of 1000


“Degradable hydrogels derived from PEG-diacrylamide for hepatic tissue engineering.”, J Biomed Mater Res A, 2015. ,
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“Patterning vascular networks in vivo for tissue engineering applications.”, Tissue Eng Part C Methods, vol. 21, no. 5, pp. 509-17, 2015. ,
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“Human iPSC-derived hepatocyte-like cells support Plasmodium liver-stage infection in vitro.”, Stem Cell Reports, vol. 4, no. 3, pp. 348-59, 2015. ,
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Highlighted in Nature Medicine


“Aberrant glycosylation promotes lung cancer metastasis through adhesion to galectins in the metastatic niche.”, Cancer Discov, vol. 5, no. 2, pp. 168-81, 2015. ,
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Featured in Nature,
Featured in Nature Reviews Cancer,
Featured in Cancer Discovery Features,
(Cover Feature)





“In vitro alterations do not reflect a requirement for host cell cycle progression during Plasmodium liver stage infection.”, Eukaryot Cell, vol. 14, no. 1, pp. 96-103, 2015. ,
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2014
“Host cell phosphatidylcholine is a key mediator of malaria parasite survival during liver stage infection.”, Cell Host Microbe, vol. 16, no. 6, pp. 778-86, 2014. ,
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“Drug-induced amplification of nanoparticle targeting to tumors”, Nano Today, vol. 9, pp. 550 - 559, 2014. ,
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“Disease detection by ultrasensitive quantification of microdosed synthetic urinary biomarkers.”, J Am Chem Soc, vol. 136, no. 39, pp. 13709-14, 2014. ,
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“Deep, noninvasive imaging and surgical guidance of submillimeter tumors using targeted M13-stabilized single-walled carbon nanotubes.”, Proc Natl Acad Sci U S A, vol. 111, no. 38, pp. 13948-53, 2014. ,
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Featured in Chemical Research in Toxicology


“New Methods in Tissue Engineering: Improved Models for Viral Infection”, Annual Review of Virology, vol. 1, pp. 475-499, 2014. ,
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“Self-titrating anticoagulant nanocomplexes that restore homeostatic regulation of the coagulation cascade.”, ACS Nano, vol. 8, no. 9, pp. 8776-85, 2014. ,
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“Microfluidic organs-on-chips.”, Nat Biotechnol, vol. 32, no. 8, pp. 760-72, 2014. ,
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Related feature in Nature


“Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems.”, Proc Natl Acad Sci U S A, vol. 111, no. 33, pp. 12193-8, 2014. ,
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'In This Issue' highlight


“Mechanisms of cooperation in cancer nanomedicine: towards systems nanotechnology.”, Trends Biotechnol, vol. 32, no. 9, pp. 448-55, 2014. ,
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“Cell and tissue engineering for liver disease.”, Sci Transl Med, vol. 6, no. 245, p. 245sr2, 2014. ,
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“Macro-to-Micro Interface for the Control of Cellular Organization”, Journal of Microelectromechanical Systems, vol. 23, pp. 391–397, 2014. ,
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“Point-of-care diagnostics for noncommunicable diseases using synthetic urinary biomarkers and paper microfluidics.”, Proc Natl Acad Sci U S A, vol. 111, no. 10, pp. 3671-6, 2014. ,
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“Micropatterned cell-cell interactions enable functional encapsulation of primary hepatocytes in hydrogel microtissues.”, Tissue Eng Part A, vol. 20, no. 15-16, pp. 2200-12, 2014. ,
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Supporting Information


“Pluripotent stem cell-derived hepatocyte-like cells.”, Biotechnol Adv, vol. 32, no. 2, pp. 504-13, 2014. ,
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“Weighing nanoparticles in solution at the attogram scale.”, Proc Natl Acad Sci U S A, vol. 111, no. 4, pp. 1310-5, 2014. ,
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“Hypoxia promotes liver-stage malaria infection in primary human hepatocytes in vitro.”, Dis Model Mech, vol. 7, no. 2, pp. 215-24, 2014. ,
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2013
“Mass-encoded synthetic biomarkers for multiplexed urinary monitoring of disease.”, Nat Biotechnol, vol. 31, no. 1, pp. 63-70, 2013. ,
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“A computational framework for identifying design guidelines to increase the penetration of targeted nanoparticles into tumors.”, Nano Today, vol. 8, no. 6, pp. 566-576, 2013. ,
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“HeLiVa platform: integrated heart-liver-vascular systems for drug testing in human health and disease.”, Stem Cell Res Ther, vol. 4 Suppl 1, p. S8, 2013. ,
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“Nanoparticles that sense thrombin activity as synthetic urinary biomarkers of thrombosis.”, ACS Nano, vol. 7, no. 10, pp. 9001-9, 2013. ,
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“Plasmonic photothermal heating of intraperitoneal tumors through the use of an implanted near-infrared source.”, ACS Nano, vol. 7, no. 9, pp. 8089-97, 2013. ,
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“Measuring growth and gene expression dynamics of tumor-targeted S. typhimurium bacteria.”, J Vis Exp, no. 77, p. e50540, 2013. ,
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“A microscale human liver platform that supports the hepatic stages of Plasmodium falciparum and vivax.”, Cell Host Microbe, vol. 14, no. 1, pp. 104-15, 2013. ,
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“Nanotechnology: emerging tools for biology and medicine.”, Genes Dev, vol. 27, no. 22, pp. 2397-408, 2013. ,
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“Nanoparticle amplification via photothermal unveiling of cryptic collagen binding sites.”, J Mater Chem B Mater Biol Med, vol. 1, no. 39, pp. 5235-5240, 2013. ,
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“Identification of small molecules for human hepatocyte expansion and iPS differentiation.”, Nat Chem Biol, vol. 9, no. 8, pp. 514-20, 2013. ,
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“Mitochondrial localization and the persistent migration of epithelial cancer cells.”, Biophys J, vol. 104, no. 9, pp. 2077-88, 2013. ,
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“Geometric control of vascular networks to enhance engineered tissue integration and function.”, Proc Natl Acad Sci U S A, vol. 110, no. 19, pp. 7586-91, 2013. ,
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“InVERT molding for scalable control of tissue microarchitecture.”, Nat Commun, vol. 4, p. 1847, 2013. ,
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Featured in Nature


“Flow-based pipeline for systematic modulation and analysis of 3D tumor microenvironments.”, Lab Chip, vol. 13, no. 10, pp. 1969-78, 2013. ,
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2012
“What is the greatest regulatory challenge in the translation of biomaterials to the clinic?”, Sci Transl Med, vol. 4, no. 160, p. 160cm14, 2012. ,
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“In Vivo Gene Expression Dynamics of Tumor-Targeted Bacteria.”, ACS Synth Biol, vol. 1, no. 10, pp. 465-470, 2012. ,
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“Genetic Circuits in Salmonella typhimurium.”, ACS Synth Biol, vol. 1, no. 10, pp. 458-464, 2012. ,
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“Bioengineering methods for analysis of cells in vitro.”, Annu Rev Cell Dev Biol, vol. 28, pp. 385-410, 2012. ,
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“A combinatorial extracellular matrix platform identifies cell-extracellular matrix interactions that correlate with metastasis.”, Nat Commun, vol. 3, p. 1122, 2012. ,
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Featured in Nature


“Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy.”, Proc Natl Acad Sci U S A, vol. 109, no. 43, pp. 17460-5, 2012. ,
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“Identification and characterization of receptor-specific peptides for siRNA delivery.”, ACS Nano, vol. 6, no. 10, pp. 8620-31, 2012. ,
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“Cancer vulnerabilities unveiled by genomic loss.”, Cell, vol. 150, no. 4, pp. 842-54, 2012. ,
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“Targeted tumor-penetrating siRNA nanocomplexes for credentialing the ovarian cancer oncogene ID4.”, Sci Transl Med, vol. 4, no. 147, p. 147ra112, 2012. ,
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“The challenges posed by cancer heterogeneity.”, Nat Biotechnol, vol. 30, no. 7, pp. 604-10, 2012. ,
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“Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues.”, Nat Mater, vol. 11, no. 9, pp. 768-74, 2012. ,
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“A biophysical indicator of vaso-occlusive risk in sickle cell disease.”, Sci Transl Med, vol. 4, no. 123, p. 123ra26, 2012. ,
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“Modeling hepatitis C virus infection using human induced pluripotent stem cells.”, Proc Natl Acad Sci U S A, vol. 109, no. 7, pp. 2544-8, 2012. ,
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2011
“Expression of paramyxovirus V proteins promotes replication and spread of hepatitis C virus in cultures of primary human fetal liver cells.”, Hepatology, vol. 54, no. 6, pp. 1901-12, 2011. ,
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“Bioresponsive mesoporous silica nanoparticles for triggered drug release.”, J Am Chem Soc, vol. 133, no. 49, pp. 19582-5, 2011. ,
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“DNA-templated assembly of droplet-derived PEG microtissues.”, Lab Chip, vol. 11, no. 17, pp. 2967-75, 2011. ,
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“Humanized mice with ectopic artificial liver tissues.”, Proc Natl Acad Sci U S A, vol. 108, no. 29, pp. 11842-7, 2011. ,
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“Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer.”, Proc Natl Acad Sci U S A, vol. 108, no. 30, pp. 12372-7, 2011. ,
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“Nanoparticles that communicate in vivo to amplify tumour targeting.”, Nat Mater, vol. 10, no. 7, pp. 545-52, 2011. ,
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“In-silico patterning of vascular mesenchymal cells in three dimensions.”, PLoS One, vol. 6, no. 5, p. e20182, 2011. ,
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“Nanoparticle-mediated delivery of siRNA targeting Parp1 extends survival of mice bearing tumors derived from Brca1-deficient ovarian cancer cells.”, Proc Natl Acad Sci U S A, vol. 108, no. 2, pp. 745-50, 2011. ,
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2010
“Gold nanorod photothermal therapy in a genetically engineered mouse model of soft tissue sarcoma”, Nano LIFE, vol. 01, no. 03n04, pp. 277 - 287, 2010. ,
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“Multiplexed, high-throughput analysis of 3D microtissue suspensions.”, Integr Biol (Camb), vol. 2, no. 10, pp. 517-27, 2010. ,
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“Ligand-clustered "patchy" nanoparticles for modulated cellular uptake and in vivo tumor targeting.”, Angew Chem Int Ed Engl, vol. 49, no. 40, pp. 7266-70, 2010. ,
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“Single cell trapping and DNA damage analysis using microwell arrays.”, Proc Natl Acad Sci U S A, vol. 107, no. 22, pp. 10008-13, 2010. ,
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“Microfluidics-integrated time-lapse imaging for analysis of cellular dynamics.”, Integr Biol (Camb), vol. 2, no. 5-6, pp. 278-87, 2010. ,
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“Effect of nanoparticle conjugation on gene silencing by RNA interference.”, J Am Chem Soc, vol. 132, no. 24, pp. 8241-3, 2010. ,
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“Targeting of drugs and nanoparticles to tumors.”, J Cell Biol, vol. 188, no. 6, pp. 759-68, 2010. ,
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“Cooperative nanoparticles for tumor detection and photothermally triggered drug delivery.”, Adv Mater, vol. 22, no. 8, pp. 880-5, 2010. ,
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“The pipeline still leaks and more than you think: a status report on gender diversity in biomedical engineering.”, Ann Biomed Eng, vol. 38, no. 5, pp. 1928-35, 2010. ,
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“Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures.”, Proc Natl Acad Sci U S A, vol. 107, no. 7, pp. 3141-5, 2010. ,
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“Real-time imaging of hepatitis C virus infection using a fluorescent cell-based reporter system.”, Nat Biotechnol, vol. 28, no. 2, pp. 167-71, 2010. ,
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“Cooperative nanomaterial system to sensitize, target, and treat tumors.”, Proc Natl Acad Sci U S A, vol. 107, no. 3, pp. 981-6, 2010. ,
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“Tissue-specific gene delivery via nanoparticle coating.”, Biomaterials, vol. 31, no. 5, pp. 998-1006, 2010. ,
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2009
“Probing nanoantenna-directed photothermal destruction of tumors using noninvasive laser irradiation”, Applied Physics Letters, vol. 95, p. -, 2009. ,
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“SERS-Coded Gold Nanorods as a Multifunctional Platform for Densely Multiplexed Near-Infrared Imaging and Photothermal Heating.”, Adv Mater, vol. 21, no. 31, pp. 3175-3180, 2009. ,
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“Silicon nanoparticles as hyperpolarized magnetic resonance imaging agents.”, ACS Nano, vol. 3, no. 12, pp. 4003-8, 2009. ,
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“Functional delivery of siRNA in mice using dendriworms.”, ACS Nano, vol. 3, no. 9, pp. 2495-504, 2009. ,
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“Microenvironmental regulation of the sinusoidal endothelial cell phenotype in vitro.”, Hepatology, vol. 50, no. 3, pp. 920-8, 2009. ,
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“Differential proteomics analysis of the surface heterogeneity of dextran iron oxide nanoparticles and the implications for their in vivo clearance.”, Biomaterials, vol. 30, no. 23-24, pp. 3926-33, 2009. ,
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“Computationally guided photothermal tumor therapy using long-circulating gold nanorod antennas.”, Cancer Res, vol. 69, no. 9, pp. 3892-900, 2009. ,
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“Systematic surface engineering of magnetic nanoworms for in vivo tumor targeting.”, Small, vol. 5, no. 6, pp. 694-700, 2009. ,
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“Biodegradable luminescent porous silicon nanoparticles for in vivo applications.”, Nat Mater, vol. 8, no. 4, pp. 331-6, 2009. ,
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“Statistical dynamics of flowing red blood cells by morphological image processing.”, PLoS Comput Biol, vol. 5, no. 2, p. e1000288, 2009. ,
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“Modulation of hepatocyte phenotype in vitro via chemomechanical tuning of polyelectrolyte multilayers.”, Biomaterials, vol. 30, no. 6, pp. 1113-20, 2009. ,
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“The compatibility of hepatocytes with chemically modified porous silicon with reference to in vitro biosensors.”, Biomaterials, vol. 30, no. 1, pp. 26-34, 2009. ,
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2008
“Micellar hybrid nanoparticles for simultaneous magnetofluorescent imaging and drug delivery.”, Angew Chem Int Ed Engl, vol. 47, no. 38, pp. 7284-8, 2008. ,
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“Protease-triggered unveiling of bioactive nanoparticles.”, Small, vol. 4, no. 9, pp. 1307-12, 2008. ,
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“T-cadherin modulates hepatocyte functions in vitro.”, FASEB J, vol. 22, no. 11, pp. 3768-75, 2008. ,
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“In vivo tumor cell targeting with "click" nanoparticles.”, Bioconjug Chem, vol. 19, no. 8, pp. 1570-8, 2008. ,
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“Magnetic Iron Oxide Nanoworms for Tumor Targeting and Imaging.”, Adv Mater, vol. 20, no. 9, pp. 1630-1635, 2008. ,
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“Combinatorial signaling microenvironments for studying stem cell fate.”, Stem Cells Dev, vol. 17, no. 1, pp. 29-39, 2008. ,
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“Microscale culture of human liver cells for drug development.”, Nat Biotechnol, vol. 26, no. 1, pp. 120-6, 2008. ,
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2007
“Nanoparticle Self-Assembly Directed by Antagonistic Kinase and Phosphatase Activities”, Advanced Materials, vol. 19, no. 21, pp. 3579–3583, 2007. ,
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“Sickle cell vasoocclusion and rescue in a microfluidic device.”, Proc Natl Acad Sci U S A, vol. 104, no. 51, pp. 20496-500, 2007. ,
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“Remotely Triggered Release from Magnetic Nanoparticles”, Advanced Materials, vol. 19, no. 22, pp. 3932–3936, 2007. ,
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“Silicon microchips for manipulating cell-cell interaction.”, J Vis Exp, no. 7, p. 268, 2007. ,
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“High-throughput analysis of signals regulating stem cell fate and function.”, Curr Opin Chem Biol, vol. 11, no. 4, pp. 357-66, 2007. ,
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“Targeted quantum dot conjugates for siRNA delivery.”, Bioconjug Chem, vol. 18, no. 5, pp. 1391-6, 2007. ,
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“Laminin and fibronectin modulate inner ear spiral ganglion neurite outgrowth in an in vitro alternate choice assay.”, Dev Neurobiol, vol. 67, no. 13, pp. 1721-30, 2007. ,
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“Multiphase electropatterning of cells and biomaterials.”, Lab Chip, vol. 7, no. 6, pp. 702-9, 2007. ,
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“Nanoparticle self-assembly gated by logical proteolytic triggers.”, J Am Chem Soc, vol. 129, no. 19, pp. 6064-5, 2007. ,
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“Micromechanical control of cell-cell interactions.”, Proc Natl Acad Sci U S A, vol. 104, no. 14, pp. 5722-6, 2007. ,
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“Microscale control of cell contact and spacing via three-component surface patterning.”, Langmuir, vol. 23, no. 8, pp. 4103-7, 2007. ,
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“Biomimetic amplification of nanoparticle homing to tumors.”, Proc Natl Acad Sci U S A, vol. 104, no. 3, pp. 932-6, 2007. ,
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“Fabrication of 3D hepatic tissues by additive photopatterning of cellular hydrogels.”, FASEB J, vol. 21, no. 3, pp. 790-801, 2007. ,
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“Assessment of hepatocellular function within PEG hydrogels.”, Biomaterials, vol. 28, no. 2, pp. 256-70, 2007. ,
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2006
“In vitro liver tissue model established from transgenic mice: role of HIF-1alpha on hypoxic gene expression.”, Tissue Eng, vol. 12, no. 11, pp. 3135-47, 2006. ,
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“Engineering tissues for in vitro applications.”, Curr Opin Biotechnol, vol. 17, no. 5, pp. 524-31, 2006. ,
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“The smart Petri dish: a nanostructured photonic crystal for real-time monitoring of living cells.”, Langmuir, vol. 22, no. 16, pp. 7084-90, 2006. ,
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“Local heating of discrete droplets using magnetic porous silicon-based photonic crystals.”, J Am Chem Soc, vol. 128, no. 24, pp. 7938-46, 2006. ,
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“Proteolytic actuation of nanoparticle self-assembly.”, Angew Chem Int Ed Engl, vol. 45, no. 19, pp. 3161-5, 2006. ,
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“Probing the role of multicellular organization in three-dimensional microenvironments.”, Nat Methods, vol. 3, no. 5, pp. 369-75, 2006. ,
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2005
“Quantum dots to monitor RNAi delivery and improve gene silencing.”, Nucleic Acids Res, vol. 33, no. 22, p. e190, 2005. ,
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“An extracellular matrix microarray for probing cellular differentiation.”, Nat Methods, vol. 2, no. 2, pp. 119-25, 2005. ,
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“Photo- and electropatterning of hydrogel-encapsulated living cell arrays.”, Lab Chip, vol. 5, no. 1, pp. 111-8, 2005. ,
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“In vitro zonation and toxicity in a hepatocyte bioreactor.”, Toxicol Sci, vol. 84, no. 1, pp. 110-9, 2005. ,
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“Hypoxic inhibition of 3-methylcholanthrene-induced CYP1A1 expression is independent of HIF-1alpha.”, Toxicol Lett, vol. 155, no. 1, pp. 151-9, 2005. ,
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2004
“Intracellular Delivery of Quantum Dots for Live Cell Labeling and Organelle Tracking”, Advanced Materials, vol. 16, pp. 961–966, 2004. ,
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“Probing the Cytotoxicity of Semiconductor Quantum Dots”, Nano Letters, vol. 4, pp. 11-18, 2004. ,
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“Manipulation of liquid droplets using amphiphilic, magnetic one-dimensional photonic crystal chaperones.”, Nat Mater, vol. 3, no. 12, pp. 896-9, 2004. ,
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“Microfabricated platform for studying stem cell fates.”, Biotechnol Bioeng, vol. 88, no. 3, pp. 399-415, 2004. ,
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“Geometric and material determinants of patterning efficiency by dielectrophoresis.”, Biophys J, vol. 87, no. 4, pp. 2131-47, 2004. ,
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“Assessing porcine liver-derived biomatrix for hepatic tissue engineering.”, Tissue Eng, vol. 10, no. 7-8, pp. 1046-53, 2004. ,
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“Three-dimensional tissue fabrication.”, Adv Drug Deliv Rev, vol. 56, no. 11, pp. 1635-47, 2004. ,
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“Exploring interactions between rat hepatocytes and nonparenchymal cells using gene expression profiling.”, Hepatology, vol. 40, no. 3, pp. 545-54, 2004. ,
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2003
“Fabrication of PLGA scaffolds using soft lithography and microsyringe deposition.”, Biomaterials, vol. 24, no. 14, pp. 2533-40, 2003. ,
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“Polymer replicas of photonic porous silicon for sensing and drug delivery applications.”, Science, vol. 299, no. 5615, pp. 2045-7, 2003. ,
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“Formation of steady-state oxygen gradients in vitro: application to liver zonation.”, Biotechnol Bioeng, vol. 82, no. 3, pp. 253-62, 2003. ,
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“Anisotropic stretch-induced hypertrophy in neonatal ventricular myocytes micropatterned on deformable elastomers.”, Biotechnol Bioeng, vol. 81, no. 5, pp. 578-87, 2003. ,
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2002
“Three-Dimensional Photopatterning of Hydrogels Containing Living Cells”, Biomedical Microdevices, vol. 4, no. 4, pp. 257 - 266, 2002. ,
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“Electro-Optical Platform for the Manipulation of Live Cells”, Langmuir, vol. 19, no. 5, pp. 1532 - 1538, 2002. ,
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“Optical Addressing of Polymer Beads for Chip-Based Systems”, Sensors and Materials, vol. 14, pp. 189–197, 2002. ,
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“Gender and achievement-related beliefs among engineering students”, Journal of Women and Minorities in Science and Engineering, vol. 8, pp. 41–52, 2002. ,
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“Microfabricated PLGA scaffolds: a comparative study for application to tissue engineering”, Materials Science and Engineering: C, vol. 20, no. 1-2, pp. 43 - 47, 2002. ,
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“Biomolecular screening with encoded porous-silicon photonic crystals.”, Nat Mater, vol. 1, no. 1, pp. 39-41, 2002. ,
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“Improving the next generation of bioartificial liver devices.”, Semin Cell Dev Biol, vol. 13, no. 6, pp. 447-54, 2002. ,
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“Engineering liver therapies for the future.”, Tissue Eng, vol. 8, no. 5, pp. 725-37, 2002. ,
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“Nanocrystal targeting in vivo.”, Proc Natl Acad Sci U S A, vol. 99, no. 20, pp. 12617-21, 2002. ,
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“Engineering protein and cell adhesivity using PEO-terminated triblock polymers.”, J Biomed Mater Res, vol. 60, no. 1, pp. 126-34, 2002. ,
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2001
“Heterogeneous integration through electrokinetic migration”, Engineering in Medicine and Biology Magazine, IEEE, vol. 20, no. 6, pp. 144-151, 2001. ,
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“Electrokinetic Assembly of Microsphere and Cellular Arrays”, Symposia LL/MM/NN/OO – Biomaterials for Drug Delivery & Tissue Engineering, 2001. ,
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“Compatibility of Primary Hepatocytes with Oxidized Nanoporous Silicon”, Advanced Materials, vol. 13, pp. 1877–1880, 2001. ,
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“Advances in bioartificial liver devices.”, Hepatology, vol. 34, no. 3, pp. 447-55, 2001. ,
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“Effects of morphological patterning on endothelial cell migration.”, Biorheology, vol. 38, no. 2-3, pp. 101-8, 2001. ,
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2000
“Xenobiotic metabolism by cultured primary porcine hepatocytes.”, Tissue Eng, vol. 6, no. 5, pp. 467-79, 2000. ,
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1999
“Tissue Engineering at the Micro-Scale”, Biomedical Microdevices, vol. 2, pp. 131-144, 1999. ,
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“Effect of cell-cell interactions in preservation of cellular phenotype: cocultivation of hepatocytes and nonparenchymal cells.”, FASEB J, vol. 13, no. 14, pp. 1883-900, 1999. ,
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“Prenatal detection and mapping of a distal 8p deletion associated with congenital heart disease.”, Prenat Diagn, vol. 19, no. 9, pp. 863-7, 1999. ,
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“Oxygen consumption characteristics of porcine hepatocytes.”, Metab Eng, vol. 1, no. 1, pp. 49-62, 1999. ,
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“Numerical model of fluid flow and oxygen transport in a radial-flow microchannel containing hepatocytes.”, J Biomech Eng, vol. 121, no. 1, pp. 58-64, 1999. ,
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1998
“Probing heterotypic cell interactions: hepatocyte function in microfabricated co-cultures.”, J Biomater Sci Polym Ed, vol. 9, no. 11, pp. 1137-60, 1998. ,
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“Microfabrication of hepatocyte/fibroblast co-cultures: role of homotypic cell interactions.”, Biotechnol Prog, vol. 14, no. 3, pp. 378-87, 1998. ,
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1997
“Engineered substrates for controlling cell-cell interactions”, Advances in Heat and Mass Transfer in Biotechnology, vol. ASME HTD-355, no. BED-37, pp. 99-103, 1997. ,
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“Controlling cell interactions by micropatterning in co-cultures: hepatocytes and 3T3 fibroblasts.”, J Biomed Mater Res, vol. 34, no. 2, pp. 189-99, 1997. ,
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1996
“Zonal liver cell heterogeneity: effects of oxygen on metabolic functions of hepatocytes”, J Cell Eng, vol. 1, pp. 125-135, 1996. ,
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1994
“Selective Adhesion of Hepatocytes on Patterned Surfaces”, Annals of the New York Academy of Sciences, vol. 745, no. 1204, pp. 187 - 209, 1994. ,
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“Oxygen is a factor determining in vitro tissue assembly: Effects on attachment and spreading of hepatocytes.”, Biotechnol Bioeng, vol. 43, no. 7, pp. 654-60, 1994. ,
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