Publications

Autonomous circadian rhythms in the human hepatocyte regulate hepatic drug metabolism and inflammatory responses
Melodi Anahtar Melodi Anahtar

Autonomous circadian rhythms in the human hepatocyte regulate hepatic drug metabolism and inflammatory responses

Sandra March, Niketa Nerurkar, Anisha Jain, Linda Andrus, Daniel Kim, Charles A. Whittaker, Edward K.W. Tan, Sabine Thiberge, Heather E. Fleming, Liliana Mancio-Silva, Charles M. Rice, and Sangeeta N. Bhatia.

Science Advances (2024)

Manuscript: (PDF)

Supplementary Materials (PDF)

News coverage:

MIT News Feature (here), AAAS Feature (here).

Read More
Priming agents transiently reduce the clearance of cell-free DNA to improve liquid biopsies
Melodi Anahtar Melodi Anahtar

Priming agents transiently reduce the clearance of cell-free DNA to improve liquid biopsies

Carmen Martin-Alonso, Shervin Tabrizi , Kan Xiong, Timothy Blewett, Sainetra Sridhar, Andjela Crnjac, Sahil Patel, Zhenyi An, Ahmet Bekdemir, Douglas Shea, Shih-Ting Wang, Sergio Rodriguez-Aponte, Christopher A. Naranjo, Justin Rhoades, Jesse D. Kirkpatrick, Heather E. Fleming, Ava P. Amini, Todd R. Golub, J. Christopher Love , Sangeeta N. Bhatia, and Viktor A. Adalsteinsson.

Science (2024)

Manuscript (PDF)

Cited by:

Tina Moser, Ellen Heitzer, Surpassing sensitivity limits in liquid biopsy. Science383,260-261 (2024). (PDF).

Sarah Crunkhorn, Improving liquid biopsy for cancer detection. Nature Reviews Drug Discovery (2024). (PDF).

News coverage:

MIT News Feature (here), Broad Press Release (here).

Read More
Inhalable point-of-care urinary diagnostic platform
Melodi Anahtar Melodi Anahtar

Inhalable point-of-care urinary diagnostic platform

Qian Zhong, Edward K. W. Tan, Carmen Martin-Alonso, Tiziana Parisi, Liangliang Hao, Jesse D. Kirkpatrick, Tarek Fadel, Heather E. Fleming, Tyler Jacks, Sangeeta N. Bhatia.

Science Advances (2024)

Manuscript (PDF)

News coverage: MIT News Feature (here), HHMI Feature (here).

Read More